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Figure 11 | Veterinary Research

Figure 11

From: Chickens treated with a nitric oxide inhibitor became more resistant to Plasmodium gallinaceum infection due to reduced anemia, thrombocytopenia and inflammation

Figure 11

Spleen and liver of aminoguanidine treated chickens have less malaria pigment during the acute phase of the infection. (A) Spleen section of untreated chickens stained with H&E, showing lymphocyte depletion (arrows). (B) Same visual field observed by polarized microscopy. (C) Spleen section of treated chickens stained with H&E, showing extensive lymphocyte depletion. (D) Same visual field observed by polarized microscopy. Note less birefringent material in treated chickens. (E) Liver section of untreated chickens, stained with H&E. An extensive area of inflammatory infiltrate can be seen (arrows) next to a vessel (arrowhead). (F) Same visual field observed by polarized microscopy. (G) Liver section stained with H&E of treated chickens. A predominantly mixed mononuclear inflammatory infiltrate can be observed (arrow). (H) Same visual field observed by polarized microscopy. Note less birefringent material in treated chickens. Bar = 50 μm.

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