Exploring the abomasal lymph node transcriptome for genes associated with resistance to the sheep nematode Teladorsagia circumcincta

Table 2 Differential expression of inflammatory cytokines and receptors in ALN as assessed by RT-qPCR.

Up-regulated genes	Fold change*	p-value	Down-regulated genes	Fold change	p-value
Resistant vs. Control
IL4	3.96	0.006	AIMP1	−3.26	0.980
IL5	2.86	0.098	BMP2	−2.67	0.914
IL10RA	2.43	0.063	CCL20	−2.57	0.119
IL13	11.92	0.001	CXCL12	−7.28	0.297
IL17B	2.06	0.104	IL2RB	−4.33	0.135
IL9R	4.01	0.254	MIF	−2.16	0.020
			TNFSF4	−3.42	0.112
			VEGFA	−4.28	0.208
Susceptible vs. Control
IL4	3.83	0.007	CCL5	−2.43	0.008
IL13	3.37	0.030	CCL11	−2.11	0.046
			CXCL10	−2.76	0.182
			CXCL12	−2.24	0.263
			CXCL9	−3.00	0.106
			CXCR1	−2.49	0.006
			CXCR3	−2.25	0.005
			IFNG	−2.14	0.135
			IL2RB	−4.71	0.100
			TNFSF10	−2.03	0.020
Resistant vs. Susceptible
CCL5	3.16	0.030	AIMP1	−2.90	0.773
CCR2	2.58	0.185	CXCL12	−3.26	0.823
CXCL9	2.92	0.165	TNFSF4	−2.13	0.424
CXCL10	3.07	0.099	VEGFA	−2.77	0.797
IFNG	2.16	0.129
IL5	3.40	0.045
IL13	3.54	0.002
IL17B	2.71	0.061
IL9R	3.77	0.200

*Fold change is the ratio of normalized mean expression between resistant, susceptible and control groups. Bold is p ≤ 0.05.

ISSN: 1297-9716