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Table 2 Differential expression of inflammatory cytokines and receptors in ALN as assessed by RT-qPCR.

From: Exploring the abomasal lymph node transcriptome for genes associated with resistance to the sheep nematode Teladorsagia circumcincta

Up-regulated genes Fold change* p-value Down-regulated genes Fold change p-value
Resistant vs. Control
IL4 3.96 0.006 AIMP1 −3.26 0.980
IL5 2.86 0.098 BMP2 −2.67 0.914
IL10RA 2.43 0.063 CCL20 −2.57 0.119
IL13 11.92 0.001 CXCL12 −7.28 0.297
IL17B 2.06 0.104 IL2RB −4.33 0.135
IL9R 4.01 0.254 MIF −2.16 0.020
    TNFSF4 −3.42 0.112
    VEGFA −4.28 0.208
Susceptible vs. Control
IL4 3.83 0.007 CCL5 −2.43 0.008
IL13 3.37 0.030 CCL11 −2.11 0.046
    CXCL10 −2.76 0.182
    CXCL12 −2.24 0.263
    CXCL9 −3.00 0.106
    CXCR1 −2.49 0.006
    CXCR3 −2.25 0.005
    IFNG −2.14 0.135
    IL2RB −4.71 0.100
    TNFSF10 −2.03 0.020
Resistant vs. Susceptible
CCL5 3.16 0.030 AIMP1 −2.90 0.773
CCR2 2.58 0.185 CXCL12 −3.26 0.823
CXCL9 2.92 0.165 TNFSF4 −2.13 0.424
CXCL10 3.07 0.099 VEGFA −2.77 0.797
IFNG 2.16 0.129    
IL5 3.40 0.045    
IL13 3.54 0.002    
IL17B 2.71 0.061    
IL9R 3.77 0.200    
  1. *Fold change is the ratio of normalized mean expression between resistant, susceptible and control groups. Bold is p ≤ 0.05.