Intravascular coagulation and morphological changes in M. suis infected pigs. Transmission electron micrographs of porcine liver and heart preparations. A, B. Heart biopsies from an M. suis-infected pig with unorganized myofibrils (MF). M. suis cells are indicated by a black arrowhead and thin endothelial cells of capillaries (c) and sinusoids (Si) with a black arrow. Scale bar = 4 μm (A); scale bar = 4 μm (B); C. Heart biopsy from an uninfected control pig. Myofibrils exhibit the typical banding pattern with alternating A and I bands. Scale bar = 4 μm. D, E. Liver preparations from an M. suis-infected pig with red blood cell (RBC) aggregates adherent to endothelial cells (ECs). Scale bar = 4 μm (D); scale bar = 1 μm (E); F. Liver preparation from an uninfected control pig. Scale bar = 4 μm. Abbreviations: Mi, mitochondria; N, nucleus; Ps, pseudopodia; RBC, red blood cell; ER, endoplasmic reticulum; V, intracellular vacuoles; and Bc, bile canaliculi.