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Table 2 CyHV-3 and host proteins identified by 2D-LC MS/MS in the supernatant of CyHV-3 infected CCB cells.

From: The IL-10 homologue encoded by cyprinid herpesvirus 3 is essential neither for viral replication in vitro nor for virulence in vivo

Database Accession number Description Predicted MW (kDa) Mascot score No. of matching spectra emPAI
   CyHV-3 proteins     
Cyprinivirus gi|129560530 ORF12, TNF receptor superfamily homologue 19.2 671 14 1.49
gi|129560652 ORF134, Interleukin 10 homologue 14.8 304 6 1.02
gi|84181525 ORF116, predicted membrane glycoprotein 30.4 185 4 0.26
gi|84181523 ORF119, putative uncharacterized protein containing an hydrophobic region 15.5 94 2 0.25
gi|129560569 ORF52, predicted membrane glycoprotein 39.2 44 1 0.10
   Host proteins (species origin)     
Bony vertebrates gi|122891218 Novel protein (zgc:103659) (Danio rerio) 51.7 410 13 0.42
gi|136429 Trypsin (Sus scrofa) 25.1 281 9 0.53
gi|297262447 Predicted keratin, type II cytoskeletal 1-like isoform 6 (Macaca mulatta) 65.3 268 3 0.12
gi|37590349 Enolase 1, alpha (D. rerio) 47.4 255 8 0.35
gi|326670662 Predicted collagen alpha-3(VI) chain-like (D. rerio) 11.3 227 8 0.17
gi|51949771 Fibronectin 1b (D. rerio) 279.3 213 8 0.08
gi|52218922 Pigment epithelium-derived factor precursor (D. rerio) 45.0 158 3 0.17
gi|416696 Beta-2-microglobulin (Cyprinus carpio) 13.5 152 8 1.79
gi|1351907 Serum albumin (Bos taurus) 71.2 149 11 0.36
gi|395744345 Predicted keratin, type II cytoskeletal 1 (Pongo abelii) 25.8 139 3 0.15
gi|229552 Albumin (B. taurus) 68.1 136 10 0.38
gi|63102189 Pgd protein (D. rerio) 53.7 134 4 0.14
gi|15718387 Gelatinase (Paralichthys olivaceus) 75.5 125 5 0.15
gi|1703244 Fructose-bisphosphate aldolase C (Carassius auratus) 39.8 124 4 0.20
gi|169154447 Fibronectin 1 (D. rerio) 275.6 117 5 0.05
gi|15149946 Procollagen type I alpha 1 chain (D. rerio) 49.4 117 5 0.34
gi|148726027 Cadherin 11, osteoblast (D. rerio) 88.9 112 5 0.13
gi|4885063 Fructose-bisphosphate aldolase C (Homo sapiens) 39.8 107 2 0.20
gi|28336 Mutant beta-actin (beta'-actin) (H. sapiens) 42.1 105 2 0.09
gi|28317 Unnamed protein product (H. sapiens) 59.7 104 3 0.13
gi|337758 Pre-serum amyloid P component (H. sapiens) 25.5 100 3 0.32
gi|223582 Histone H4 (H. sapiens) 11.2 99 5 0.84
gi|47971186 Carp C1q-like molecule (C. carpio) 20.3 98 2 0.19
gi|223061 Ubiquitin (Salmo sp.) 8.5 92 4 0.31
gi|27806751 Alpha-2-HS-glycoprotein precursor (B. taurus) 39.2 90 4 0.32
gi|47086029 Myristoylated alanine-rich C kinase substrate 2 (D. rerio) 21.0 86 2 0.18
gi|2133885 N-cadherin precursor (D. rerio) 87.4 80 3 0.09
gi|18859555 Wnt inhibitory factor 1 precursor (D. rerio) 43.2 79 3 0.09
gi|34595971 Prion-like protein 1 (C. carpio) 55.6 75 2 0.14
gi|208609649 Collagen type I alpha 3 (C. auratus) 137.7 75 1 0.03
gi|47085905 14-3-3 protein beta/alpha-B (D. rerio) 27.5 75 3 0.47
gi|6644111 Nucleoside diphosphate kinase-Z1 (D. rerio) 17.4 72 2 0.22
gi|16974825 Chain A, Solution Structure Of Calcium-Calmodulin N-Terminal Domain (H. sapiens) 8.5 70 2 0.49
gi|41152406 FK506 binding protein 1A, 12kDa (D. rerio) 11.8 69 3 1.39
gi|189527793 Predicted neuroblast differentiation-associated protein AHNAK (D. rerio) 642.1 65 2 0.01
gi|37492 Alpha-tubulin (H. sapiens) 50.8 65 2 0.07
gi|33989505 Tissue inhibitor of metalloproteinase 2b (D. rerio) 24.7 64 2 0.15
gi|8176557 Heart fatty acid binding protein (Anguilla japonica) 15.3 61 1 0.26
gi|37181 Tissue inhibitor of metalloproteinases, Type-2 (H. sapiens) 21.4 59 2 0.18
gi|437972 Fibrillin-2 (H. sapiens) 334.8 59 1 0.01
gi|37367051 Osteopontin (D. rerio) 23.2 53 1 0.16
gi|45544646 Cold inducible RNA binding protein isoform 2 (D. rerio) 19.2 52 2 0.20
gi|51328294 Fstl1b protein (D. rerio) 39.6 50 1 0.09
gi|82245450 Triosephosphate isomerase B (D. rerio) 27.1 50 1 0.14
gi|34014734 Clusterin (D. rerio) 52.5 50 1 0.07
gi|47228578 Unnamed protein product (Tetraodon nigroviridis) 77.5 49 1 0.05