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Table 3 Summary of experiments assessing the level of cross protection to lethal RHDV infection provided by RCV-A1

From: The non-pathogenic Australian rabbit calicivirus RCV-A1 provides temporal and partial cross protection to lethal Rabbit Haemorrhagic Disease Virus infection which is not dependent on antibody titres

Study No. Protection rate N RCV-A1 infection Time post RCV-A1 infection RHDV challenge Reference
1 52% 11/21 Natural infection Unknown One dose 1000 LD 50, IM [14]
2 36% 22/61 Natural infection Unknown One dose 1500 LD 50, PO [15]
3 33% 25/77 Natural infection Unknown One dose 1500 LD 500, PO [29]
4 50% 2/4 Experimental infection 4 weeks One dose 500 LD 50, PO [19]
5a 38% 3/8 Natural infection < 8 weeks One dose 500 LD 50, PO and/or continuous exposure (contaminated environment) This report
5b 13% 1/8 Natural infection 8 - 10 weeks One dose 500 LD 50, PO and/or continuous exposure (contaminated environment) This report
5c 6% 1/18 Natural infection > 10 weeks One dose 500 LD 50, PO and/or continuous exposure (contaminated environment) This report
  1. IM, Intra muscular, PO, Peroral.