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Table 1 The neutralizing titer, T-lymphocyte proliferation and protection of cattle

From: Foot-and-mouth disease virus-like particles produced by a SUMO fusion protein system in Escherichia coli induce potent protective immune responses in guinea pigs, swine and cattle

Group

No

Neutralizing titer

T-lymphocyte proliferation (SI)

Protection

Rate of protection

PD50

9 dpi

16 dpi

21 dpi

21 dpi

10 dpc

One dose

#4536

2.408

2.709

2.107

1.989

yes

100(5/5)

6.34

 

#4572

2.107

2.408

2.408

1.602

yes

  
 

#4574

2.408

2.709

2.107

1.373

yes

  
 

#4590

2.107

2.408

2.408

1.586

yes

  
 

#4592

2.408

2.709

2.408

1.625

yes

  

1/3 dose

#4501

1.806

1.806

1.806

1.587

yes

80(4/5)

 
 

#4561

1.204

1.505

1.806

1.512

yes

  
 

#4575

1.806

2.107

2.107

1.721

yes

  
 

#4593

1.806

1.806

1.806

1.889

yes

  
 

#4597

1.204

1.204

1.505

1.353

no

  

1/9 dose

#4534

1.505

1.505

1.806

1.351

no

40(2/5)

 
 

#4563

1.505

1.505

1.204

1.886

yes

  
 

#4564

1.204

1.505

1.505

1.375

no

  
 

#4594

1.806

1.806

1.806

1.558

yes

  
 

#4598

1.204

1.505

1.505

1.397

no

  

Healthy cattle

#4576

0.778

0.903

0.778

1.052

no

0(0/5)

 
 

#4580

0.903

0.778

0.602

1.115

no

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