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Table 1 The neutralizing titer, T-lymphocyte proliferation and protection of cattle

From: Foot-and-mouth disease virus-like particles produced by a SUMO fusion protein system in Escherichia coli induce potent protective immune responses in guinea pigs, swine and cattle

Group No Neutralizing titer T-lymphocyte proliferation (SI) Protection Rate of protection PD50
9 dpi 16 dpi 21 dpi 21 dpi 10 dpc
One dose #4536 2.408 2.709 2.107 1.989 yes 100(5/5) 6.34
  #4572 2.107 2.408 2.408 1.602 yes   
  #4574 2.408 2.709 2.107 1.373 yes   
  #4590 2.107 2.408 2.408 1.586 yes   
  #4592 2.408 2.709 2.408 1.625 yes   
1/3 dose #4501 1.806 1.806 1.806 1.587 yes 80(4/5)  
  #4561 1.204 1.505 1.806 1.512 yes   
  #4575 1.806 2.107 2.107 1.721 yes   
  #4593 1.806 1.806 1.806 1.889 yes   
  #4597 1.204 1.204 1.505 1.353 no   
1/9 dose #4534 1.505 1.505 1.806 1.351 no 40(2/5)  
  #4563 1.505 1.505 1.204 1.886 yes   
  #4564 1.204 1.505 1.505 1.375 no   
  #4594 1.806 1.806 1.806 1.558 yes   
  #4598 1.204 1.505 1.505 1.397 no   
Healthy cattle #4576 0.778 0.903 0.778 1.052 no 0(0/5)  
  #4580 0.903 0.778 0.602 1.115 no