Transgenically mediated shRNAs targeting conserved regions of foot-and-mouth disease virus provide heritable resistance in porcine cell lines and suckling mice

Table 3 Survival rates of suckling mice from different transgenic mouse lines challenged with serotype O FMDV

Mouse line	Dosage(LD₅₀)	Transgenic suckling mice Survival/Total (%)	Non-transgenic littermates Survival/Total (%)
N3D2B-18	10	0/9 (0)	1/16 (6.3)
	6	3/21 (14.3)	3/33 (9.1)
	3	7/26 (26.9)	0/27 (0)
N3D2B-81	10	0/9 (0)	0/22 (0)
	6	3/11 (27.3)	0/23 (0)
	3	7/17 (41.2)	2/9 (22.2)

ISSN: 1297-9716