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Table 3 Survival rates of suckling mice from different transgenic mouse lines challenged with serotype O FMDV

From: Transgenically mediated shRNAs targeting conserved regions of foot-and-mouth disease virus provide heritable resistance in porcine cell lines and suckling mice

Mouse line Dosage(LD50) Transgenic suckling mice
Survival/Total (%)
Non-transgenic littermates
Survival/Total (%)
N3D2B-18 10 0/9 (0) 1/16 (6.3)
  6 3/21 (14.3) 3/33 (9.1)
  3 7/26 (26.9) 0/27 (0)
N3D2B-81 10 0/9 (0) 0/22 (0)
  6 3/11 (27.3) 0/23 (0)
  3 7/17 (41.2) 2/9 (22.2)