|
Transcription and activation pathways
| | |
|
NFKBIA
|
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
3.60
|
4.53
|
|
BIRC3
|
Baculoviral IAP repeat-containing protein 3
|
3.10
|
3.19
|
|
ZNFX1
|
NFX1-type zinc finger-containing protein 1
| |
3.11
|
|
ZNHIT3
|
Zinc finger HIT domain-containing protein 3
|
2.48
|
3.08
|
|
IKBKAP
|
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
|
2.52
|
2.33
|
|
TRIM21
|
Tripartite motif-containing protein 21
|
1.61
|
2.26
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.02
|
1.60
|
|
NFKB2
|
Nuclear factor of κ light polypeptide gene enhancer in B-cells 2
|
1.78
|
1.94
|
|
JAK2
|
Janus kinase 2
|
1.90
|
1.85
|
|
DUSP1
|
Dual specificity phosphatase 1
| |
1.85
|
|
FOS
|
V-fos
| |
-2.01
|
|
PLK2
|
Serum-inducible kinase, transcript variant 1,PLK2
|
-1.50
| |
|
Cytokines and chemokines, growth factors
| | |
|
CCL5
|
RANTES
|
7.10
|
20.52
|
|
CCL20
|
Chemokine (C-C motif) ligand 20
|
19.42
|
19.37
|
|
CXCL8
|
Chemokine (C-X-C motif) ligand 8, Interleukin-8
|
8.53
|
13.96
|
|
CXCL5
|
Chemokine (C-X-C motif) ligand
|
4.75
|
7.96
|
|
CCL2
|
Chemokine (C-C motif) ligand 2
| |
6.38
|
|
CXCL2
|
Chemokine (C-X-C motif) ligand 2
| |
5.06
|
|
CXCL1
|
Chemokine (C-X-C motif) ligand 1
|
4.93
| |
|
IL6
|
Interleukin 6
|
6.64
|
4.85
|
|
CXCL3
|
Chemokine (C-X-C motif) ligand 3
|
3.15
|
3.60
|
|
IL1B
|
Interleukin 1, beta
|
5.01
|
3.32
|
|
IFNB
|
Interferon beta precursor
|
4.89
|
3.25
|
|
TNFSF13B
|
Tumor necrosis factor (ligand) superfamily, member 13 (BAFF)
|
2.96
| |
|
IL2
|
Interleukin 2
|
4.30
|
2.86
|
|
CCL16
|
Chemokine (C-C motif) ligand 16
|
2.60
|
2.77
|
|
CSF2
|
Colony stimulating factor 2 (granulocyte-macrophage)
|
1.69
|
2.10
|
|
IL23A
|
Interleukin 23, alpha subunit p19
| |
2.06
|
|
CTGF
|
Connective tissue growth factor
|
-1.92
| |
|
TGFB2
|
Transforming growth factor beta-2 precursor
| |
-1.46
|
|
Type I IFN-related genes
| | |
|
IFIT3
|
Interferon-induced protein with tetratricopeptide repeats 3
|
3.02
|
7.92
|
|
MX1
|
Myxovirus (influenza virus) resistance 1
|
1.84
|
2.93
|
|
IFIH1
|
Interferon induced with helicase C domain 1
|
2.65
|
4.10
|
|
ISG15
|
ubiquitin-like modifier
|
2.46
|
3.69
|
|
GBP1
|
Interferon-induced guanylate-binding protein 1
|
2.17
|
3.56
|
|
TNFSF10
|
Tumor necrosis factor ligand superfamily member 10 (TRAIL)
|
2.02
|
3.13
|
|
IFI44
|
Similar to Interferon-induced protein 44
| |
3.23
|
|
OAS1
|
2′-5′-oligoadenylate synthetase 1
|
1.61
|
3.15
|
|
IFI27L1
|
Interferon alpha-inducible protein 27-like protein 1
| |
2.88
|
|
IRF7
|
Interferon regulatory factor 7
|
1.45
|
2.75
|
|
TRIM21
|
Tripartite motif-containing protein 21
|
1.61
|
2.26
|
|
GVIN1
|
GTPase, very large interferon inducible 1
| |
2.21
|
|
STAT2
|
Signal transducer and activator of transcription 2
| |
2.01
|
|
STAT1
|
Signal transducer and activator of transcription 1
| |
1.96
|
|
IRF2
|
Interferon regulatory factor 2
| |
1.84
|
|
Immune defense response
| | |
|
NOS2A
|
Nitric oxide synthase 2A (inducible)
|
5.57
|
7.45
|
|
S100A8
|
Calcium-binding protein A8, calgranulin A
|
2.87
|
7.00
|
|
CFB
|
Complement factor B
|
3.39
|
5.02
|
|
S100A9
|
Calcium-binding protein A9, calgranulin B
|
2.40
|
4.59
|
|
CD83
|
Cell surface protein HB15
|
5.50
|
3.40
|
|
C2
|
C2 Complement component 2
|
1.79
|
2.64
|
|
ICAM1
|
Intercellular adhesion molecule 1
|
2.50
| |
|
LTF
|
Lactotransferrin
| |
2.47
|
|
PLAT
|
Plasminogen activator, tissue type
|
1.93
|
2.11
|
|
PLAUR
|
Urokinase plasminogen activator surface receptor
|
2.11
|
1.96
|
|
CAMP
|
Cathelicidin antimicrobial peptide
| |
1.89
|
|
TLR4
|
Toll-like receptor 4
|
1.62
|
1.81
|
|
MMP9
|
Matrix metallopeptidase 9
| |
1.77
|
|
CD74
|
Major histocompatibility complex, class II invariant chain
| |
1.75
|
|
BNBD10
|
Beta-defensin 10
|
1.59
|
1.67
|
|
Stress response
| | |
|
SOD2
|
Superoxide dismutase 2
|
3.19
|
5.05
|
|
SGK1
|
Serum/glucocorticoid regulated kinase 1
|
1.81
|
4.79
|
|
PARP14
|
Poly (ADP-ribose) polymerase family, member 14
| |
2.95
|
|
Cell growth and cycle, apoptosis
| | |
|
IGFBP3
|
Insulin-like growth factor binding protein-3
|
2.38
|
5.27
|
|
EIF4E
|
Translation initiation factor 4E
|
2.32
|
5.20
|
|
CASP4
|
Caspase-4 Precursor
|
1.60
|
3.04
|
|
CASP8
|
Caspase-8 precursor
|
1.58
|
2.29
|
|
IER3
|
Immediate early response 3
|
2.09
| |
|
TNFRSF6
|
TNF receptor superfamily, member 6 (FAS)
|
1.82
|
1.86
|
|
CDK2AP1
|
Cyclin-dependent kinase 2 associated protein 1
| |
-1.66
|
|
EI24
|
Etoposide-induced protein 2.4 homolog
| |
-1.65
|
