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Table 1 Pathological changes in the gizzard

From: Quantity of virulent fowl adenovirus serotype 1 correlates with clinical signs, macroscopical and pathohistological lesions in gizzards following experimental induction of gizzard erosion in broilers

   Macroscopical lesions Histological lesions
Group dpi Koilin layer Gizzard mucosa Inclusion bodies in glandular epithelium In-situ hybridization
SPFB 3 0/5 (0.0)a 0/5 (0.0) 0/5 (0.0) 0/5
7 5/5 (1.8) 5/5 (1.8) 5/5 (2.6) 5/5
10 5/5 (2.4) 5/5 (1.0) 1/5 (0.2) 1/5
14 5/5 (1.8) 2/5 (0.4) 0/5 (0.0) NEb
17 4/5 (0.8) 3/5 (0.6) 0/5 (0.0) NE
CB 3 0/5 (0.0) 0/5 (0.0) 0/5 (0.0) 0/5
7 3/5 (0.6) 3/5 (0.8) 4/5 (1.6) 4/5
10 4/5 (1.2) 5/5 (1.6) 5/5 (2.0) 5/5
14 5/5 (2.2) 4/5 (0.8) 0/5 (0.0) NE
  17 5/5 (1.6) 4/5 (0.8) 0/5 (0.0) NE
  1. Specific-pathogen-free (SPFB) and commercial (CB) broilers orally infected with virulent FAdV-1 at 3, 7, 10, 14 and 17 days post infection (dpi).
  2. a No. birds positive/no. birds examined (mean lesion scores in parenthesis; no lesion = 0, mild lesions = 1, moderate lesions = 2 and severe lesions = 3).
  3. b NE – not examined.