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Table 1 List of genes up- or down-regulated in the chicken cecum after infection with Salmonella Enteritidis arranged according to their maximal fold up- or down-regulation after infection with wild type Salmonella Enteritidis (column max fold SE wt)

From: Chicken innate immune response to oral infection with Salmonella enterica serovar Enteritidis

Gene Max NI# Min NI Max SE Min SE Max fold WT fold SPI1 fold
      SE wt$ 4 dpi& 4 dpi&
MMP7 0.078 (12) 0.001 (29) 8.98 (5) 0.001 (1) 5952 (10) 1578 35.2
IgG 5.02 (25) 0.006 (2) 36.7 (25) 0.009 (1) 442 (10) 33.2 1.63
IRG1 0.005 (2) 0.001 (11) 0.69 (5) 0.003 (1) 425 (7) 222 4.61
SAA 0.25 (2) 0.018 (9) 15.9 (5) 0.065 (1) 382 (5) 106 5.02
ExFABP 1.06 (18) 0.150 (9) 75.3 (5) 0.369 (1) 366 (5) 56.8 4.80
IL-22 0.005 (12) 0.0004 (10) 0.39 (5) 0.001 (1) 355 (10) 46.9 2.69
TRAP6 0.39 (2) 0.011 (15) 5.76 (5) 0.029 (25) 194 (5) 37.3 2.19
MRP126 0.16 (2) 0.003 (29) 1.96 (5) 0.018 (25) 194 (11) 14.3 2.11
IFNγ 0.001 (18) 0.0001 (11) 0.035 (5) 0.0002 (1) 183 (11) 62.8 1.39
IL1β 0.018 (18) 0.002 (1) 0.74 (5) 0.002 (1) 134 (3) 29.1 1.59
iNOS 0.019 (1) 0.008 (9) 1.99 (7) 0.019 (1) 151 (7) 47.9 2.84
ES1 2.06 (2) 0.055 (29) 39.6 (4) 0.178 (1) 139 (11) 17.4 2.21
LYG2 0.26 (7) 0.015 (22) 5.82 (3) 0.031 (25) 130 (3) 24.5 3.09
IFIT5 0.56 (12) 0.003 (1) 1.28 (3) 0.003 (1) 124 (3) 42.4 2.62
IL-17 0.014 (2) 0.0003 (29) 0.095 (3) 0.001 (22) 120 (11) 6.72 1.12
AVD 2.07 (2) 0.20 (29) 103.1 (5) 0.207 (1) 116 (9) 29.6 3.24
AH221 0.73 (18) 0.12 (1) 23.4 (5) 0.119 (1) 108 (5) 42.9 1.90
serpin B 0.096 (2) 0.002 (29) 0.54 (5) 0.009 (25) 101 (5) 18.4 1.45
TGM4 0.092 (12) 0.005 (6) 0.92 (5) 0.014 (1) 68 (6) 30.4 1.99
IgA 6.04 (18) 0.003 (2) 23.4 (22) 0.005 (3) 49 (3) 16.6 1.86
EPSTI1 0.39 (12) 0.015 (1) 0.74 (4) 0.015 (1) 33 (3) 12.9 1.40
IL-8 0.15 (6) 0.004 (29) 1.08 (4) 0.007 (1) 31 (11) 4.54 1.24
C3 0.092 (2) 0.019 (10) 0.78 (11) 0.044 (1) 29 (10) 9.7 1.53
mucin-2 0.37 (3) 0.018 (9) 0.77 (4) 0.124 (6) 20 (11) 1.01 0.94
PTGDS 1.50 (9) 0.12 (1) 17.8 (5) 0.117 (1) 19 (5) 14.9 1.70
ITGLB2 (CD18) 0.084 (22) 0.031 (3) 0.46 (11) 0.045 (18) 14 (11) 9.40 1.04
HPX 0.19 (7) 0.025 (12) 0.91 (5) 0.071 (25) 13 (5) 5.06 1.10
ASL2 0.46 (2) 0.15 (29) 2.26 (4) 0.289 (1) 11 (10) 3.74 1.17
HCLS1 0.25 (29) 0.088 (5) 1.11 (10) 0.107 (1) 10 (11) 5.41 1.13
TAP1 0.443 (22) 0.087 (3) 2.26 (7) 0.104 (1) 10 (4) 13.7 1.37
STAT1 0.31 (12) 0.059 (9) 1.03 (3) 0.164 (1) 9.2 (9) 8.61 1.25
RSFR 0.96 (8) 0.40 (1) 7.19 (5) 0.397 (1) 9.1 (5) 6.41 1.19
MEG1 0.49 (22) 0.090 (3) 1.80 (5) 0.115 (1) 7.0 (5) 8.22 0.92
STAT3 0.64 (18) 0.37 (3) 1.28 (7) 0.537 (5) 2.2 (3) 2.91 1.00
AQP8 33.4 (22) 14.9 (1) 17.6 (25) 0.290 (5) 97 (5) 18.90 1.80
ADH1B 9.46 (7) 3.42 (2) 4.66 (25) 0.100 (5) 75 (5) 16.23 1.55
FABP1 6.11 (22) 1.98 (11) 8.48 (22) 0.119 (5) 47 (5) 5.49 1.32
RALDH1 18.6 (22) 9.17 (2) 12.6 (1) 0.404 (5) 39 (5) 12.87 1.43
unchar. oxidoreductase 5.84 (12) 0.80 (4) 4.25 (22) 0.192 (5) 28 (5) 7.14 1.26
CALB1 24.2 (1) 8.20 (2) 24.2 (1) 0.785 (5) 19 (5) 13.78 1.88
ALDOB 1.66 (22) 0.32 (2) 0.58 (22) 0.037 (5) 19 (10) 6.71 0.99
SULT1C3 21.9 (4) 7.20 (29) 16.0 (1) 1.081 (5) 18 (5) 8.04 1.86
HPGD 4.62 (7) 1.58 (1) 2.77 (2) 0.396 (5) 10 (7) 8.87 1.29
  1. # Maximal or minimal expression levels observed in the non-infected or Salmonella Enteritidis infected chickens as determined in the time-dependent study; numbers in brackets indicate the day of life when the appropriate value was recorded.
  2. $ Maximal fold upregulation or downregulation and the day when recorded in the time-dependent study. The downregulated genes are at the bottom of the table starting with AQP8.
  3. & Fold up or downregulations 4 days post-infection of chickens with wild-type Salmonella Enteritidis and the SPI1 mutant.