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Table 1 KEGG Pathways generated by STRING

From: Salmonella enterica Typhimurium infection causes metabolic changes in chicken muscle involving AMPK, fatty acid and insulin/mTOR signaling

   24 h 96 h 1 week 3 weeks
Pathway ID Pathway name # Peptides p-value (FDR) # Peptides p-value (FDR) # Peptides p-value (FDR) # Peptides p-value (FDR)
hsa05221 Acute myeloid leukemia 4 0.0227 3 0.0344 2 0.228 3 0.0785
hsa04520 Adherens junction 4 0.0506 2 0.340 2 0.332 4 0.0302
hsa04920 Adipocytokine signaling pathway 6 0.0023   N/S 4 0.0131 7 0.0003
hsa04360 Axon guidance 6 0.0191 4 0.0432   N/S   N/S
hsa04662 B cell receptor signaling pathway 5 0.0123 3 0.0559   N/S 4 0.0297
hsa04020 Calcium signaling pathway 5 0.166   N/S 6 0.0095   N/S
hsa04062 Chemokine signaling pathway 4 0.469 5 0.0344 4 0.126   N/S
hsa05220 Chronic myeloid leukemia 4 0.0452 4 0.0103 2 0. 318 6 0.0012
hsa05210 Colorectal cancer   N/S 4 0.0066   N/S 3 0.0969
hsa05213 Endometrial cancer 3 0.0976 4 0.0047   N/S   N/S
hsa04012 ErbB signaling pathway 8 0.0001 7 0.0000 4 0.0167 5 0.0097
hsa04664 Fc epsilon RI signaling pathway 7 0.0006 5 0.0029   N/S 6 0.0018
hsa04666 Fc gamma R-mediated phagocytosis 4 0.0979 4 0.0224   N/S 5 0.0148
hsa04510 Focal adhesion 8 0.0123 6 0.0115   N/S 7 0.0154
hsa05214 Glioma 7 0.0001 3 0.0432 6 0.0001 5 0.0033
hsa00010 Glycolysis/Gluconeogenesis 5 0.0064 3 0.0432 3 0.0586 6 0.0008
hsa04912 GnRH signaling pathway 7 0.0015 5 0.0047 4 0.0245 5 0.0151
hsa05410 Hypertrophic cardiomyopathy (HCM) 3 0.264   N/S 3 0.106 6 0.0018
hsa04910 Insulin signaling pathway 13 0.0000 10 0.0000 7 0.0003 16 0.0000
hsa04730 Long-term depression 4 0.0449 3 0.0537 4 0.0113   N/S
hsa04010 MAPK signaling pathway 14 0.0001 13 0.0000 4 0.318 11 0.0011
hsa05218 Melanoma 4 0.0443 4 0.0095 4 0.0113 5 0.0043
hsa04150 mTOR signaling pathway 6 0.0004 3 0.0309   N/S 5 0.0018
hsa04722 Neurotrophin signaling pathway 6 0.0176 6 0.0020 5 0.0113 7 0.0018
hsa05223 Non-small cell lung cancer 5 0.0048 3 0.0362   N/S 4 0.0151
hsa05212 Pancreatic cancer 4 0.0418 3 0.0476   N/S 4 0.0227
hsa05200 Pathways in cancer   N/S   N/S 6 0.0639 9 0.0151
hsa04914 Progesterone-mediated oocyte maturation 5 0.0176   N/S   N/S 5 0.0097
hsa05215 Prostate cancer 5 0.0192 4 0.0173 4 0.0169 5 0.0107
hsa04810 Regulation of actin cytoskeleton 6 0.104 6 0.0115   N/S 6 0.0591
hsa05211 Renal cell carcinoma 4 0.0446 5 0.0018   N/S 4 0.0254
hsa05222 Small cell lung cancer   N/S   N/S 2 0.397 6 0.0020
hsa04660 T cell receptor signaling pathway 6 0.0123 4 0.0344   N/S 3 0.332
hsa04620 Toll-like receptor signaling pathway 5 0.0403 5 0.0058   N/S 6 0.0043
hsa04270 Vascular smooth muscle contraction 5 0.0452 3 0.139   N/S 4 0.105
hsa04370 VEGF signaling pathway 6 0.0023   N/S   N/S 4 0.0302
  1. Peptides that displayed a statistically significant change in phosphorylation state were input into the STRING database for each time point. Generated pathways that displayed a p-value of less than 0.05 (FDR corrected) are listed. Pathways that displayed statistical significance at three or more time points are shown in bold. N/S indicates that the pathway is Non-significant as no peptides were found within the pathway.