Figure 8From: Pathogenic mechanisms implicated in the intravascular coagulation in the lungs of BVDV-infected calves challenged with BHV-1Immunohistochemical detection of iNOS and COX-2 in the lungs of BVDV pre-infected calves challenged with BHV-1.1. Numerous immunolabeled septal MΦs iNOS-positive were observed in the lungs of calves inoculated only with BVDV (0 dpi of BVDV/BHV-1 group) (A), versus a minor number of these cells at 4 dpi BHV-1.1 (B). Pulmonary parenchyma of calves inoculated only with BVDV (0 dpi of BVDV/BHV-1 group) showed an absence of MΦs positive for COX-2 Ab (C), compared with numerous immunolabeled MΦs COX-2-positive observed in the sites of inflammation at 4 dpi (D).Back to article page