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Figure 2 | Veterinary Research

Figure 2

From: Pathogenic mechanisms implicated in the intravascular coagulation in the lungs of BVDV-infected calves challenged with BHV-1

Figure 2

Immunohistochemical detection of pulmonary platelet clusters in calves with and without pre-existing BVDV challenged with BHV-1.1. Immunohistochemical study of the lung in these animals revealed that the calves of the BVDV/BHV-1 group showed a great quantity of Factor VIII-positive clusters of platelets in some pulmonary venules and capillaries at 4 dpi (A), compared with minor changes present in the BHV-1 group (B), where IMΦs and periarterial MΦs were observed engulfing positive granular material. Moreover, the calves of the BVDV/BHV-1 group showed lower quantities of platelet clusters at 14 dpi (C), with this lesion in the BHV-1 group being almost inexistent at this time (D).

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Veterinary Research

ISSN: 1297-9716