|
Anamnestic data
|
Mouse bioassay (Tgbov XV)
|
|---|
|
Cow
|
mpi
|
Clinical status
|
Results by IHC*
|
Jejunum A
|
Jejunum B
|
Ileum
|
Ileocaec-junct
|
|---|
|
Brain (Obex)
|
Ileum/Ileocaec-junct
|
|---|
|
KT32
|
4
|
Control
|
--
|
−−/−−
|
0/11
|
0/15
|
0/11
|
0/15
|
|
IT04
|
1
|
Preclinical
|
--
|
−−/−−
|
0/10
|
0/13
|
0/13
|
0/11
|
|
IT44
|
1
|
Preclinical
|
--
|
−−/−−
|
0/13
|
0/15
|
0/12
|
0/13
|
|
IT19
|
4
|
Preclinical
|
--
|
+/−−
|
0/12
|
0/13
|
9/15 (380 ± 65)
|
0/14
|
|
IT45
|
4
|
Preclinical
|
--
|
+/−−
|
0/15
|
0/14
|
11/13 (366 ± 46)
|
0/12
|
|
IT26
|
24
|
Late preclinical
|
+
|
++/−−
|
8/14 (440 ± 96)
|
0/13
|
14/14 (317 ± 36)
|
2/11 (414, 526)
|
|
IT24
|
24
|
Preclinical
|
--
|
++/−−
|
1/13 (533)
|
0/14
|
15/15 (328 ± 52)
|
12/14 (325 ± 45)
|
|
IT47
|
24
|
Preclinical
|
--
|
+++/−−
|
1/15 (448)
|
2/12 (434, 707)
|
13/13 (267 ± 20)
|
3/12 (354,536,725)
|
|
IT58
|
24
|
Preclinical
|
--
|
−−/+
|
0/12
|
0/15
|
2/12 (442, 445)
|
0/15
|
- *All jejunal samples were negative in IHC, mpi: months post infection; IHC: Immunohistochemistry; -- negative result, +/++ mild/moderate accumulation of PrPSc, Mouse bioassay results relying on PTA-Western blot of mouse brains: the first numbers indicate the number of positive mice/inoculated mice, the number in brackets indicates the mean incubation period in days post infection and the standard deviation.
