Skip to main content

Table 1 Anamnestic data (immunohistochemical results are from[10]) and mouse bioassay results of all cattle examined

From: Complementary studies detecting classical bovine spongiform encephalopathy infectivity in jejunum, ileum and ileocaecal junction in incubating cattle

Anamnestic data Mouse bioassay (Tgbov XV)
Cow mpi Clinical status Results by IHC* Jejunum A Jejunum B Ileum Ileocaec-junct
Brain (Obex) Ileum/Ileocaec-junct
KT32 4 Control -- −−/−− 0/11 0/15 0/11 0/15
IT04 1 Preclinical -- −−/−− 0/10 0/13 0/13 0/11
IT44 1 Preclinical -- −−/−− 0/13 0/15 0/12 0/13
IT19 4 Preclinical -- +/−− 0/12 0/13 9/15 (380 ± 65) 0/14
IT45 4 Preclinical -- +/−− 0/15 0/14 11/13 (366 ± 46) 0/12
IT26 24 Late preclinical + ++/−− 8/14 (440 ± 96) 0/13 14/14 (317 ± 36) 2/11 (414, 526)
IT24 24 Preclinical -- ++/−− 1/13 (533) 0/14 15/15 (328 ± 52) 12/14 (325 ± 45)
IT47 24 Preclinical -- +++/−− 1/15 (448) 2/12 (434, 707) 13/13 (267 ± 20) 3/12 (354,536,725)
IT58 24 Preclinical -- −−/+ 0/12 0/15 2/12 (442, 445) 0/15
  1. *All jejunal samples were negative in IHC, mpi: months post infection; IHC: Immunohistochemistry; -- negative result, +/++ mild/moderate accumulation of PrPSc, Mouse bioassay results relying on PTA-Western blot of mouse brains: the first numbers indicate the number of positive mice/inoculated mice, the number in brackets indicates the mean incubation period in days post infection and the standard deviation.