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Table 1 Immunohistochemical labelling (filaggrin, loricrin), histopathology and transepidermal water loss

From: The effect of Psoroptes ovis infestation on ovine epidermal barrier function

Time 0 h 1 hpi 3 hpi 6 hpi 24 hpi
Filaggrin (average MFI/mm) 189 (34.43-751.01)* 236.16 (93.57-469.30)* 160.95 (23.69-370.62)* N/A 11.49 (0–44.59)*
Loricrin (average MFI/mm) 122.06 (83.79-227.59)* 225.15 (69.60-402.44)* 171.71 (0.09-305.21)* N/A 55.28 (0–213.95)*
Mean PMN cell count per mm2 9.13 (0.97-31.91)* 92.09 (12.57-207.93)* 1099.83 (410.06-1959.38)* N/A 1174.16 (1098.65-2330.75)*
TEWL (g/m2h) 20.54 (13.62-29.48)* 598.67 (598–662)* 585.17 (597.67-637)* 516.46 (403.83-597.33)* 396.75 (331.17-481)*
  1. Mean fluorescence intensity (MFI)/mm epithelium for filaggrin and loricrin and mean polymorphonuclear (PMN) cell counts /mm2 at time 0, 1, 3 and 24 hours post-infestation (hpi). Transepidermal water loss (TEWL) g/m2h at 0,1,3,6 and 24 hpi. *Reference range.