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Table 1 Immunohistochemical labelling (filaggrin, loricrin), histopathology and transepidermal water loss

From: The effect of Psoroptes ovis infestation on ovine epidermal barrier function

Time

0 h

1 hpi

3 hpi

6 hpi

24 hpi

Filaggrin (average MFI/mm)

189 (34.43-751.01)*

236.16 (93.57-469.30)*

160.95 (23.69-370.62)*

N/A

11.49 (0–44.59)*

Loricrin (average MFI/mm)

122.06 (83.79-227.59)*

225.15 (69.60-402.44)*

171.71 (0.09-305.21)*

N/A

55.28 (0–213.95)*

Mean PMN cell count per mm2

9.13 (0.97-31.91)*

92.09 (12.57-207.93)*

1099.83 (410.06-1959.38)*

N/A

1174.16 (1098.65-2330.75)*

TEWL (g/m2h)

20.54 (13.62-29.48)*

598.67 (598–662)*

585.17 (597.67-637)*

516.46 (403.83-597.33)*

396.75 (331.17-481)*

  1. Mean fluorescence intensity (MFI)/mm epithelium for filaggrin and loricrin and mean polymorphonuclear (PMN) cell counts /mm2 at time 0, 1, 3 and 24 hours post-infestation (hpi). Transepidermal water loss (TEWL) g/m2h at 0,1,3,6 and 24 hpi. *Reference range.
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Veterinary Research

ISSN: 1297-9716