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Figure 1 | Veterinary Research

Figure 1

From: Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome

Figure 1

Pigmented pathological changes in the hearts of CMS-diseased fish. (A-D) Field outbreak. (E-F) Experimental infection study. (A) A severely affected area of the atrium where hypertrophic endocardial cells formed tubes filled with heavily pigmented cells interpreted as melanomacrophages. H&E, bar = 50 μm. (B) Morphological variation of the melanomacrophages includes elongated, dendritic-shaped cells and rounded macrophage-like cells containing abundant amounts of melanin. H&E, bar = 10 μm. (C-D) Microdissection from an area with accumulations of melanomacrophages, before and after laser capture respectively. Haematoxylin, bar = 50 μm. (E-F) Melanin deposits in severely affected atrial areas with CMS-associated pathological changes, 24 and 27 wpc, respectively. H&E, bar 50 μm.

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Veterinary Research

ISSN: 1297-9716