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Table 4 Serum Hp and SAA concentrations during common sheep diseases and conditions

From: Two major ruminant acute phase proteins, haptoglobin and serum amyloid A, as serum biomarkers during active sheep scab infestation

Infection/Condition Mean Hp (mg/mL) Mean SAA (μg/mL)
Early gestationa (n = 10) 0.33 ± 0.01 9.34 ± 2.14
Late gestationb (n = 10) 0.52 ± 0.08 17.09 ± 7.77
Gastro-intestinal nematodesc (n = 6) 0.04 ± 0.03 0.30 ± 0.01
Liver Fluke (Fasciola hepatica)d (n = 6) 2.85 ± 0.02 0.22 ± 0.01
Sucking lice (Linognathus spp.)e (n = 4) 0.52 ± 0.51 68.47 ± 22.33
Chewing lice (Bovicola ovis)e (n = 4) 0.65 ± 0.31 193.36 ± 135.81
Orf (n = 6)f 0.21 ± 0.01 0.93 ± 0.53
Johnes diseaseg (n = 6) 2.25 ± 0.34 21.43 ± 10.47
  1. Hp (mg/mL ± SEM) measured by colorimetric assay (ReactivLab) and SAA (μg/mL ± SEM) assessed by SAA ELISA (Tridelta Development Ltd). All samples were assayed for individual animals in duplicate. aEarly gestation was within 1 week of conception and blate gestation was 1 week prior to expected lambing date (samples from Moredun Research Institute (MRI)). cSamples from sheep with field-acquired gastro-intestinal nematode (GIN) infections were from Firth Mains Farm, UK (MRI); species included Teladorsagia circumcincta and Nematodirus battus.dSamples were taken from UK sheep with field-acquired infections of liver fluke (samples provide by Dr H McDougall, MRI); esamples from lice infected but P. ovis-uninfested sheep (provided by Prof. N. Sargison, R(D)SVS, UK; fsamples from sheep infected experimentally with orf virus or gMycobacterium avium subspecies paratuberculosis (MRI).