Two major ruminant acute phase proteins, haptoglobin and serum amyloid A, as serum biomarkers during active sheep scab infestation

Table 3 Distribution of sheep into “normal” and “elevated” groups for Pso o 2-specific serum IgG across the time course of a primary infestation with Psoroptes ovis and treatment with an endectocide (PIT trial)

Week	0	1	2	3	4	5	6*	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Normal	12	9	4	3	1	1	0	0	0	0	0	0	0	1	1	1	2	4	5	5	6
Elevated	0	3	8	9	11	11	12	12	12	12	12	12	12	11	11	11	10	8	7	7	6

* All animals were treated with injectable endectocide at week 6 post-infestation. In this analysis the animals were described as being “normal” as in day 0 (pre-infestation) or “elevated”. As the results showed a normal distribution, all values above the 0.999 quantile of the distribution were considered to be elevated, giving a 99.9% specificity and undefined sensitivity.

ISSN: 1297-9716