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Table 3 Distribution of sheep into “normal” and “elevated” groups for Pso o 2-specific serum IgG across the time course of a primary infestation with Psoroptes ovis and treatment with an endectocide (PIT trial)

From: Two major ruminant acute phase proteins, haptoglobin and serum amyloid A, as serum biomarkers during active sheep scab infestation

Week 0 1 2 3 4 5 6* 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Normal 12 9 4 3 1 1 0 0 0 0 0 0 0 1 1 1 2 4 5 5 6
Elevated 0 3 8 9 11 11 12 12 12 12 12 12 12 11 11 11 10 8 7 7 6
  1. * All animals were treated with injectable endectocide at week 6 post-infestation. In this analysis the animals were described as being “normal” as in day 0 (pre-infestation) or “elevated”. As the results showed a normal distribution, all values above the 0.999 quantile of the distribution were considered to be elevated, giving a 99.9% specificity and undefined sensitivity.