Biomarker | Week | 0 | 1 | 2 | 3 | 4 | 5 | 6** | 6.5 | 7 | 7.5 | 8 |
---|
Hp
| Normal* | 12 | 11 | 11 | 11 | 10 | 4 | 2 | 2 | 7 | 11 | 12 |
Elevated | 0 | 1 | 1 | 1 | 2 | 8 | 10 | 10 | 5 | 1 | 0 |
SAA
| Normal | 12 | 9 | 10 | 11 | 4 | 0 | 0 | 7 | 11 | 12 | 12 |
Elevated | 0 | 3 | 2 | 1 | 8 | 12 | 12 | 5 | 1 | 0 | 0 |
- * The status of APP levels in sheep sera (n = 12 for each time point) was determined by comparison to pre-infestation levels using the R Statistical Package.
- ** All sheep were treated with an injectable endectocide at week 6 post-infestation. In these analyses the animals were described as being “normal” as in day 0 (pre-infestation) or “elevated”. As the results showed a normal distribution, all values above the 0.999 quantile of the distribution were considered to be elevated, giving a 99.9% specificity and undefined sensitivity.