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Table 3 Results of Wb and IHC analyses of the Q/Q 222 goats.

From: Resistance to classical scrapie in experimentally challenged goats carrying mutation K222 of the prion protein gene

Apparatus Central Nervous System Peripheral Nervous System
Organs/Tissues Brainstem Cerebellum Occipital
cortex
Parietal cortex Temporal cortex Frontal cortex Pyriform lobus Mesence -
phalon
Talamus Basal
nuclei
Cervical spinal cord Thoracic spinal cord Lumbar spinal cord Optic nerve Brachial nerve Sciatic nerve
ID sample #1 + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
  #12 + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
  #14 + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
  #18 + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
  #VA2 + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
positive/
tested
5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5 5/5
method Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb Wb Wb
Apparatus Lymph reticular System Respiratory tract Digestive apparatus
Organs/Tissues Tonsil Mandibular lymph node Retro-
pharingeal
lymph node
Mesenteric lymph node Spleen Ileo-ciecal valve Third
eyelid
Olfactory tract Trachea Lung Salivary glands Esophagus Liver Rumen Omasum Reticulum
ID sample #1 + + + + + + + + + + + + + + + - - + + - - + +
  #12 + + + + + + + + + + + - - - + - - - + - - + +
  #14 + + + + + - + + + + + + - - + - - - - - - + +
  #18 + + + + + + + + + + + + + + + - - - - - - - -
  #VA2 + + + + + + + + + + + + - - - - - - - - - - -
positive/
tested
5/5 5/5 5/5 5/5 5/5 4/5 5/5 5/5 5/5 5/5 5/5 4/5 2/5 2/5 4/5 0/5 0/5 1/5 2/5 0/5 0/5 3/5 3/5
method Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb IHC Wb Wb Wb Wb Wb Wb Wb Wb Wb
Apparatus Gastrointestinal tract Muscles Miscellaneous
Organs/Tissues Abomasum Duodenum Jejunum Ileum Caecum Rectum Tongue Masseter muscle Biceps brachii muscle Triceps femoris muscle Heart Eye Kidney Urinary bladder Mammary gland Adrenal
gland
ID sample #1 - + + + + + - + + + - + + + - -
  #12 - + + + + + + + + + + + - - - -
  #14 - + + + + + + - - + + + - - / -
  #18 - - - - - - - - - - - - - - - -
  #VA2 - + + + + - + - - - - - - - - -
positive/
tested
0/5 4/5 4/5 4/5 4/5 3/5 3/5 2/5 2/5 3/5 2/5 3/5 1/5 1/5 0/4 0/5
method Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb Wb
  1. +: positive result; -: negative result