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Table 2 Lymph node palpation scores from DNA-immunized dogs with experimental T. cruzi infection

From: Plasmid DNA immunization with Trypanosoma cruzi genes induces cardiac and clinical protection against Chagas disease in the canine model

Group Dog Lymph node inflammation (score)1 and percentage of dogs from each group with lymphadenomegaly
Basal t1 % Postimmunization t2 % Acute stage t3 %
pBCSP 1 0 0 0 50 0 67
2 0   0   0  
3 0   0   1  
4 0   2   1  
5 0   1   1  
6 0   1   2  
pBCSSP4 1 0 0 0 50 1 100*
2 0   1   2  
3 0   2   1  
4 0   1   1  
5 0   0   2  
6 0   0   2  
pBK-CMV 1 0 0 0 17 0 83*
2 0   0   1  
3 0   0   1  
4 0   0   2  
5 0   1   1  
6 0   0   1  
SS mock-immunized 1 0 0 0 0 1 100*
2 0   0   1  
3 0   0   1  
4 0   0   1  
5 0   0   1  
  6 0   0   1  
  1. 1The severity of inflammation in lymph nodes was scored on a scale from 0 to 2. A score of 0 indicated normal; 1, slightly swollen; and 2, very enlarged (scores of 1 and 2 were considered to be indicative of lymphadenomegaly). baseline = t1, prior to the start of the immunization, Postimmunization = t2, before the infection at 15 days post-immunization, and Acute stage = t3, at 30 days post-infection. Popliteal, submaxillary, axillary and inguinal lymph nodes were palpated and means were compared with the Kruskal-Wallis test. Differences were considered as significant when P ≤ 0.05.