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Figure 3 | Veterinary Research

Figure 3

From: Mitigating an undesirable immune response of inherent susceptibility to cutaneous leishmaniosis in a mouse model: the role of the pathoantigenic HISA70 DNA vaccine

Figure 3

Mice vaccinated with pCMV-HISA70m2A showed low tissue arginase activity at the site of infection as well as impaired nitrite production. (A) BALB/c mice were sacrificed at 7 weeks pi and arginase activity was determined in infected footpad homogenates. (B) In the same experiments, nitrite levels were assayed in medium from cultures of DLN draining the infection site (see Materials and Methods). Results shown are means and SD (bars) for groups of mice (n = 6) from two independent experiments. Asterisks indicate *P < 0.05 with respect to both groups of control mice.

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Veterinary Research

ISSN: 1297-9716