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Table 1 Experimental design

From: Susceptibility to scrapie and disease phenotype in sheep: cross-PRNP genotype experimental transmissions with natural sources

Recipient

AAS inoculum

VVC inoculum

codon 136

po

sc

po

sc

Total

Suffolk AA*

3sh

 

5 ht

5ht

13

Suffolk AA

3hm

 

5 ht

5ht

13

Cheviot AA

5 hm

5 hm

3 ht

 

13

Cheviot VA

5 sh

5 sh

3 sh

 

13

Cheviot VV

5 ht

5 ht

3 hm

 

13

Total

21

15

19

10

65

  1. po, “per os” (oral route); sc, subcutaneous route. *codon 171 genotype of those recipients was RQ; all others were QQ. With regard to Prnp codon 136, transmissions are: hm, homologous; sh, semi-homologous; ht, heterologous.