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Table 4 Mortality and gross lesion in the chickens post challenge

From: Construction of a Salmonella Gallinarum ghost as a novel inactivated vaccine candidate and its protective efficacy against fowl typhoid in chickens

Groupa Challengeb
Gross lesiond Bacterial recovery
Mortality (%) Liver Spleen Liver Spleen
Positive No. Positive No.
A 11/15 (73)c 2. 2.16 ± 1.46e** 1.70 ± 1.46** 0/5f 0/5
B 2/15 (14) 1.06 ± 0.96 0.66 ± 1.12 0/5 0/5
C 1/15 (6.6) 0.60 ± 0.98 0.53 ± 0.83 0/5 0/5
D 1/15 (6.6) 0.53 ± 0.89 0.53 ± 0.93 0/5 0/5
  1. a Immunization was performed at day 7 of age with the Salmonella Gallinarum ghost strain and the groups were designated as group A (non vaccinated), group B (orally immunized), group C (immunized subcutaneously) and group D (immunized intramuscularly). Fifteen birds were allocated per group.
  2. b Challenge was performed with a wild type Salmonella Gallinarum strain using 1 × 106 CFU after 21 days post vaccination.
  3. c Number of dead birds upon challenge.
  4. d Gross lesion was observed at day14 post challenge.
  5. e Group lesion score (Mean ± SD).
  6. f Number of positive samples after enrichment culture. All values were considered to be significant if p ≤ 0.05 or 0.01.* p < 0.05, **p < 0.01 vs. non vaccinated group A.