Skip to main content

Table 1 Experimental design

From: Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection

  Groups 1stChallenge*
(0 pi)
2ndChallenge*
(84 pi)
Experiment 1 20 pigs A strain 3262 Group A + A (n = 4)
Homologous challenge: strain 3262
14 pigs Group A + B (n = 4)
   Heterologous challenge: strain 3267
C1 Placebo Group C1 + B (n = 2)
  6 pigs††   naïve controls: strain 3267
Experiment 2 11 pigs B strain 3267 Group B + B (n = 4)
Homologous challenge: strain 3267
8 pigs Group B + A (n = 3**)
   Heterologous challenge: strain 3262
C2 Placebo Group C2 + A (n = 3)
  3 pigs   naïve controls: strain 3262
  1. * Inoculation was performed intranasally (2 mL; 1 mL/nostril) with a dosis of 5 × 105.0 TCID50/mL of the corresponding strain.
  2. ** One pig died at 17 pi in the first inoculation.
  3. † Six pigs were euthanized; three at 15 pi and three at 35 pi.
  4. †† Four pigs were euthanized: two at 15 pi and two at +35 pi.