Figure 1
From: What have we learned from brucellosis in the mouse model?
Replication profiles of B. abortus in mice spleens. (A) Spleen replication curves of virulent (2308 strain), vaccine-attenuated (S19 strain) and non-virulent (bvrS mutant) B. abortus strains during 36 weeks after inoculation in CD-1 mice. The abscissas axis (time after infection) of the inserted panel is expressed in logarithmic scale, to allow a better understanding of the initial phases of infection. The different phases of the infection (I, onset of infection; II, acute phase; III, chronic steady phase; IV, chronic declining phase) are depicted by the discontinuous vertical lines. (B) Spleen replication curves of virulent B. abortus 2308 strain in susceptible BALB/c and resistant C57BL/10 mice (adapted from [35], with permission).