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Table 3 Differential protein expression of differentiated IPEC-J2 cells after exposure to T-2 toxin.

From: T-2 toxin induced Salmonella Typhimurium intoxication results in decreased Salmonella numbers in the cecum contents of pigs, despite marked effects on Salmonella-host cell interactions

Protein name* Function* Protein ratio treated/untreated IPEC-J2 cells on the T-test approach Protein ratio treated/untreated IPEC-J2 cells on the log*log approach
Cytochrome c oxidase subunit VIIc {N-terminal} This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. 0.6 0.6
Microsomal glutathione S-transferase 3 Functions as a glutathione peroxidase. 0.6 0.6
PREDICTED: similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) When phosphorylated, plays a role in filament reorganization. 0.7 0.7
Myristoylated alanine-rich C-kinase substrate Myristoylated alanine-rich C-kinase substrate is a filamentous (F) actin cross-linking protein. 0.7 0.7
Annexin A4 Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. 0.7 0.7
Chain A, Bovine Mitochondrial F1-Atpase Complexed With Aurovertin B Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane. 0.7 0.8
Protein S100-A16 Calcium-binding protein. Binds one calcium ion per monomer. 0.8 0.8
Putative beta-actin Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. 0.8 0.7
Cysteine and glycine-rich protein 1 isoform 1 Encodes a member of the cysteine-rich protein (CSRP) family that includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. 1.2 1.2
Heat shock protein 60 Implicated in mitochondrial protein import and macromolecular assembly. 1.2 1.2
PREDICTED: similar to nucleolin-related protein isoform 3 Plays a role in different steps in ribosome biogenesis. 1.2 1.2
Heterogeneous nuclear ribonucleoprotein F Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. 1.2 1.2
Heat shock protein 10 Essential for mitochondrial protein biogenesis, together with chaperonin 60. 1.2 1.2
Thymosin beta-10 Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. 1.2 1.2
Thioredoxin-related transmembrane protein 1 May participate in various redox reactions. 1.3 1.3
Glutathione S-transferase P Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. 1.3 1.3
14-3-3 protein sigma Adapter protein implicated in the regulation of a large spectrum of both general and specialized signalling pathway. of G2/M progression. 1.3 1.3
Elongation factor 1-beta Elongation factor 1-beta and Elongation factor 1-delta stimulate the exchange of GDP bound to Elongation factor 1-alpha to GTP. 1.3 1.3
Profilin Binds to actin and affects the structure of the cytoskeleton. 1.5 1.5
Cyclophilin A or Peptidyl-prolyl cis-trans isomerase A Peptidyl-prolyl isomerase accelerates the folding of proteins. 1.6 1.6
Branched-chain-amino-acid aminotransferase, cytosolic Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. 1.6 1.6