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Table 3 Association between gene expression and BRD outcome

From: Stress significantly increases mortality following a secondary bacterial respiratory infection

Dead1 Alive1
Gene Day 0 2 Day 4 3 Day 0 Day 4
2'5'OAS 2.5 ± 1.14 0.0 ± 1.2** 3.6 ± 2.9 1.2 ± 1.5*
IL-β 6.9 ± 0.8 6.6 ± 0.8 7.0 ± 0.9 6.9 ± 0.5
TNF-α 6.0 ± 0.4 4.8 ± 0.5** 6.0 ± 0.5 5.1 ± 0.5*
IL-10 8.0 ± 0.8 5.6 ± 0.4** 8.4 ± 0.5 6.4 ± 0.3*§§
CD14 4.3 ± 0.7 3.1 ± 0.6** 4.2 ± 0.4 4.3 ± 0.7§§
TLR4 4.0 ± 0.8 2.9 ± 0.6** 4.2 ± 0.5 4.0 ± 0.6§§
  1. 1Data sorted for animals that either died (Dead) or survived (Alive) following M. haemolytica aerosol challenge.
  2. 2PBMC isolated from calves prior to BHV-1 infection.
  3. 3PBMC isolated from calves 4 days post-BHV-1 infection prior to M. haemolytica infection.
  4. 4Data presented are mean ΔC ± 1SD with lower Ct value corresponding to greater transcript abundance.
  5. *P < 0.05 when Day 4 compared to Day 0 within group; **P < 0.01 when Day 4 compared to Day 0 within group; §§ P < 0.01 when Day 4 values compared across groups.