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Table 3 Association between gene expression and BRD outcome

From: Stress significantly increases mortality following a secondary bacterial respiratory infection

Dead1

Alive1

Gene

Day 0 2

Day 4 3

Day 0

Day 4

2'5'OAS

2.5 ± 1.14

0.0 ± 1.2**

3.6 ± 2.9

1.2 ± 1.5*

IL-β

6.9 ± 0.8

6.6 ± 0.8

7.0 ± 0.9

6.9 ± 0.5

TNF-α

6.0 ± 0.4

4.8 ± 0.5**

6.0 ± 0.5

5.1 ± 0.5*

IL-10

8.0 ± 0.8

5.6 ± 0.4**

8.4 ± 0.5

6.4 ± 0.3*§§

CD14

4.3 ± 0.7

3.1 ± 0.6**

4.2 ± 0.4

4.3 ± 0.7§§

TLR4

4.0 ± 0.8

2.9 ± 0.6**

4.2 ± 0.5

4.0 ± 0.6§§

  1. 1Data sorted for animals that either died (Dead) or survived (Alive) following M. haemolytica aerosol challenge.
  2. 2PBMC isolated from calves prior to BHV-1 infection.
  3. 3PBMC isolated from calves 4 days post-BHV-1 infection prior to M. haemolytica infection.
  4. 4Data presented are mean ΔC ± 1SD with lower Ct value corresponding to greater transcript abundance.
  5. *P < 0.05 when Day 4 compared to Day 0 within group; **P < 0.01 when Day 4 compared to Day 0 within group; §§ P < 0.01 when Day 4 values compared across groups.