Skip to main content

Table 2 Effect of stress on gene expression following BHV-1 infection

From: Stress significantly increases mortality following a secondary bacterial respiratory infection

  WMS1 PA1
Gene Day 0 2 Day 4 3 Day 0 Day 4
2'5'OAS 3.3 ± 2.84 0.9 ± 1.2* 2.7 ± 2.1 0.0 ± 1.5**
IL-β 6.8 ± 0.9 6.7 ± 0.8 7.0 ± 0.8 6.7 ± 0.6
TNF-α 6.1 ± 0.4 4.8 ± 0.7** 6.0 ± 0.4 4.9 ± 0.3**
IL-10 8.2 ± 0.8 5.7 ± 0.6** 8.1 ± 0.6 6.1 ± 0.3**
CD14 4.3 ± 0.7 3.4 ± 1.0* 4.2 ± 0.4 3.8 ± 0.7
TLR4 4.1 ± 0.9 3.2 ± 0.9* 4.0 ± 0.4 3.6 ± 0.6*
  1. 1Weaned and maternal separation (WMS) and pre-adapted (PA) calves (n = 10/group).
  2. 2PBMC isolated from calves prior to BHV-1 infection.
  3. 3PBMC isolated from calves 4 days post-BHV-1 infection and prior to M. haemolytica infection.
  4. 4Data presented are mean ΔCt ± 1SD with lower Ct value corresponding to greater transcript abundance.
  5. *p < 0.05 when Day 4 compared to Day 0 within each group; **P < 0.01 when Day 4 compared to Day 0 within each group.