Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Susceptibility of some mouse strains used as models of non-pregnancy-associated L. monocytogenes infection, measured as median lethal dose (LD50)

From: Animal models of listeriosis: a comparative review of the current state of the art and lessons learned

mouse strain LD50range (in CFU) reported in the literature Recognized mouse phenotype
  oral/intragastric intravenous   intraperitonial   
  LD 50 (strain) Reference LD 50 (strain) Reference LD 50 (strain) Reference  
A/J 106(a) [137] 103(b, d) [138, 141] < 107- 1011(b, d,e, i) [142, 143] susceptible
A/Tru × C57Bl/67    104(b) [144]    -
A/Tru × C57Bl/64    106(b) [144]    -
A/Tru × C57Bl/68    105(b) [144]    -
A/WySn    104(d) [138]    -
BALB/c    103(b, d) [138, 145] 105(i) [147] susceptible
    104(c) [146]    
    105(f, i) [139]    
B10.A    105(b,d) [138, 141]    resistant
B10.D2/Sn    105(b, d) [138, 141]    resistant
CBA    103(d) [138]    susceptible
C3HeB/FeJ      104(i) [148] susceptible
C57BL/6 103(b) [145] 103(b) [145]    resistant
  108(a) [137] 105(b) [149]    
  > 1010(b) [149] 106(d, f, i) [138, 139]    
C57BL/6 × BALB/c    103(b) [42]    intermediate
    104(d) [138]    
C57BL/6 × DBA/2 N    104(b) [150] 107- 109(b, e, i) [143] intermediate
C57BL/10Sn    105(b) [141]    resistant
DBA/2 J    103(b) [141]    susceptible
ddY3 104(g) [127]      -
ddY4 >109(g) [127]      -
ICR    105(d) [151] 104- 107(a,d,e,i) [152] intermediate
      104- >108(b,d,i) [19, 153]  
      105- >109(a,d,e,i) [154]  
Inbred white (Washington State University)      105- 107(c) [155] -
NCR1 101- 105(d, e, i) [17]    101- 105(d, e) [17] -
NCR 103- 106(d, e,i) [17]    102- 106(d, e,i) [17] -
NMRI5    104(f) [156, 157] 10 4 - 10 12 [158] -
    104- 1012(f,g,h,i) [158] (f,g,h,i)   
Swiss    105(b) [159]    -
Swiss-Webster      101- 105(i) [115] -
      105- 107(c) [155]  
Swiss white      107(a,d,e) [18] -
Porton >1010(b,d,e,i) [160]      -
129 Sv × C57BL/6      104(b) [161] intermediate
iFABP-hEcad2 ~1010(b) [149]      transgenic
E16PmEcad6 n/a       transgenic
  1. Animals represent non-pregnant adults unless stated otherwise.
  2. 1body weights ranging from 10 - 20 grams; 2(C57BL/6 J × SJL/J) background; 3suckling mice; 4adult mice; 5derived from swiss-type mouse; 6only competitive indexing experiments performed; 7juvenile mice; 8geriatric mice
  3. L. monocytogenes strains:
  4. (a) L.monocytogenes Scott A (serotype 4b); (b) L.monocytogenes EGD (serotype 1/2a); (c) L. monocytogenes 10403S (serotype 1/2a); (d) human clinical isolate; (e) food isolate; (f) L. monocytogenes 4b isolate; (g) L. monocytogenes 1b isolate; (h) L. monocytogenes 3a isolate; (i) other or not specified L. monocytogenes isolate.