Schematic diagram showing the positions of identified SNPs within the bovine TLR1 gene. Open box represents coding exon (CDS = 2379 bp), grey boxes represent non-coding untranslated exonic regions (UTR). A TLR1 protein domain architecture diagram, designed using web-based programmes [47, 48], is illustrated below the CDS. The non-synonymous +1762A > G SNP (in bold), is located within the transmembrane domain (vertical black bar). LRR - leucine-rich repeat domains (19 in total), LRR C -leucine-rich repeat C terminal domain, TIR - Toll-Interleukin 1-resistance domain. Sequence shown from Btau_4.0 sequence (NC_007304.4), bta6: 60355 k-60363 k. Boxed SNPs have been sequenced extensively for trait associations.