Figure 2

Histopathological analysis of skin fragments from left footpad of BALB/c (A, B, C and D) and C3H.He (E, F, G and H) mock-infected mice, 30 days after mock infection. A. Normal morphology of footpad is observed. The integrity of the epidermis and dermis, the presence of adipocytes and ducts of regular glands can be seen (HE). B. Elastic (thin arrow), elaunin (thick arrow) and oxytalan (arrow) fibres with normal morphology and location are also observed (Weigert). C: Picrosirius red in non-polarized light showing the regular arrangement of the skin showing epidermis, dermis and hypodermis. D. Picrosirius red in polarized light shows the normal arrangement of type I collagen (orange and yellow) and type III (green). E. Normal morphology of footpad is observed. The organization of the epidermis and dermis were maintained, the presence of adipocytes and ducts of regular glands can also be seen (HE). F. Elastic fibres (thin arrow), elaunin fibres (thick arrow) with normal morphology and location are noted (Weigert). G. Picrosirius red in non-polarized light showing the regular organization of the skin showing epidermis, dermis and hypodermis. H. Picrosirius red polarized light shows the normal organization of type I collagen (orange and yellow) and type III (green).