From: Antimicrobial peptides and proteins of the horse - insights into a well-armed organism
Peptide family Peptide | Mass [kDa] | Charge (at pH 7.5) | Specificity | Salt dependency | Citation |
---|---|---|---|---|---|
Cathelicidins | Â | Â | Â | Â | Â |
eCATH-1 [GenBank: CAA12226] | 3.1 | 8.8 | Gram-positive/negative bacteria Fungi | no no | |
eCATH-2 [GenBank: CAA12227] | 3.6 | 2.8 | Gram-positive/negative bacteria Fungi | no yes | |
eCATH-3 [GenBank: CAA12228] | 4.7 | 7.0 | Gram-positive/negative bacteria Fungi | yes yes | |
eCATH-4 [GenBank: XP_001495199.2] | n. d. | n. d. | n. d. | Â | this review |
EA-CATH-1 [GenBank: ACN93988.1] | 3.1 | 6.8 | Gram-positive/negative bacteria Fungi | no no | [43] |
Defensins | Â | Â | Â | Â | Â |
DEFB1 [GenBank: AAO32801] | 4.0 | 5.2 | n. d. | Â | [36] |
DEFL2 [GenBank: CAJ01792] | 4.5 | 6.5 | n. d. | Â | |
DEFL3 [GenBank: CAJ01793] | 4.2 | 5.6 | n. d. | Â | |
DEFB103 [GenBank: CAJ01801] | 4.7 | 9.2 | n.d. | Â | |
DEFA1 [GenBank: ABP96800] | 4.1 | 6.3 | Gram-positive/negative bacteria Yeast | yes yes | |
DEFA2 to 29 [GenBank: ACV49728-ACV49755] | 3.6 - 5.5 | 2.3 - 9.2 | n. d. | Â | [41] |
Neutrophil antimicrobial peptides | Â | Â | Â | Â | Â |
eNAP-1 [GenBank: AAB22706] | 7.2 | n. d. | Gram-positive/negative bacteria | n. d. | [33] |
eNAP-2 [GenBank: AAB24353] | 6.5 | n. d. | Gram-positive/negative bacteria | n. d. | |
Lysozymes | Â | Â | Â | Â | Â |
Equine lysozyme [Swiss-Prot: P11376] | 14.7 | 2.2 | Gram-positive/negative bacteria | n. d. | |
NK-lysins | Â | Â | Â | Â | Â |
Equine NK-lysin [GenBank: AAN10122] | 9.2 | 7.2 | n. d. | Â | |
Psoriasin (S100A7) | Â | Â | Â | Â | Â |
Psoriasin 1 [GenBank: CAH03717] | 11.3 | -6.2 | Escherichia coli | n.d. | |
Hepcidin | Â | Â | Â | Â | Â |
Equine hepcidin [GenBank: XM_001491610.2] | 2.8 | 1.1 | n. d. | Â | [158] |