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Table 2 Distribution of 39 genotype-I PRRSV isolates according to their cytokine profiles.

From: Cytokine profiles and phenotype regulation of antigen presenting cells by genotype-I porcine reproductive and respiratory syndrome virus isolates

  BMDC SwC3+
IL-10 pg/mL* NA NA 183 ± 137 (280-86) 410 ± 98 (522-297) NA NA 323 ± 259 (752-119) 501 ± 363 (1352-77)
TNF-α Pg/mL* NA 502 ± 293 (1070-91) NA 432 ± 300 (941-201) NA 879 ± 715 (2,039-103) NA 1321 ± 939 (2847-229)
Total strains 13 19 2 5 5 13 4 17
  1. *Cytokine-inducing profiles for IL-10 and TNF-α were obtained using bone marrow-derived dendritic cells and sorted SwC3+ peripheral blood mononuclear cells inoculated at a multiplicity of infection of 0.01. Values in the table show the average, standard deviation and range (pg/mL) of the concentrations in cell culture supernatants obtained for a set of strains inducing a given cytokine.