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Table 3 Immunohistochemical and western blot analyses of PrPSc in tissue samples obtained from cattle intracerebrally challenged with H-type BSE

From: Experimental H-type bovine spongiform encephalopathy characterized by plaques and glial- and stellate-type prion protein deposits

Tissue Case code
  7749 9458 0728
  IHC WB IHC WB IHC WB
Central nervous system       
   Cerebral cortex + + + + + +
   Obex + + + + + +
   Cerebrum + + + + + +
   Spinal cord + + + + + +
Peripheral nervous system       
   Cauda equina + + + + + +
   Dorsal root ganglia + + + + + +
   Trigeminal ganglia + + + + + +
   Cranial cervical ganglia - + - + - +
   Stellate ganglia - + - + - +
   Sympathetic trunk - + - + - +
   Celiac-mesenteric ganglion complex - + - + - +
   Vagus nerve - + - + - +
   Facial nerve - + - + - -
   Hypoglossal nerve - + - + - -
   Phrenic nerve - + - + - +
   Accessory nerve - - - + - +
   Suprascapular nerve - + - + - +
   Brachial plexus - + - + - +
   Median nerve - + - + - +
   Radial nerve - + - + - +
   Sciatic nerve - + - + - +
   Tibial nerve - + - + - +
   Optic nerve + + + + + +
   Retina + + + + + +
   Pituitary gland + + + + + +
   Adrenal gland - + - + - +
Lymphoid tissues       
   Spleen - - - - - -
   Tonsils (palatine, pharyngeal, lingual) - - - - - -
   Thymus - - - - - -
   Parotid lymph node - - - - - -
   Mandibular lymph node - - - - - -
   Lateral retropharyngeal lymph node - - - - - -
   Superficial cervical lymph node - - - - - -
   Brachiocephalic lymph node - - - - - -
   Axillary lymph node - - - - - -
   Superficial inguinal lymph node - - - - - -
   Subiliac lymph node - - - - - -
   Popliteal lymph node - - - - - -
   Hepatic lymph node - - - - - -
   Internal iliac lymph node - - - - - -
   External iliac lymph node - - - - - -
   Mesenteric lymph node - - - - - -
  1. IHC, immunohistochemistry; WB, western blotting; +, positive for PrPSc; -, negative for PrPSc