Table 1 Characteristics of the 11 antibodies and the epitope location of the bovine PrP
Antibodies | Epitope | Clonality | Immunogen | Source** | ||
|---|---|---|---|---|---|---|
| Â | Â | Location | Type* | Â | Â | Â |
N-terminal region | SAF32 | 62-92 | L | Monoclonal | SAF from infected hamster brain | SPI-Bio (Montigny-le-Bretonneux, France) |
| Â | B103 | 103-121 | L | Polyclonal | Cattle recPrP | FUJIREBIO (Tokyo, Japan) [34] |
| Â | F89/160.1.5 | 148-155 | L | Monoclonal | Cattle recPrP | VMRD (Pullman, WA, USA) |
| Â | T1 | 149-153 | L | Monoclonal | Mouse recPrP | Dr Tagawa |
| Â | 12F10 | 154-163 | L | Monoclonal | Hamster recPrP | SPI-Bio |
Core region | SAF54 | 168-172 | L | Monoclonal | SAF from infected hamster brain | SPI-Bio |
| Â | 44B1 | 168-242 | DC | Monoclonal | Mouse recPrP | Dr Horiuchi [33] |
| Â | SAF84 | 175-180 | L | Monoclonal | SAF from infected hamster brain | SPI-Bio |
| Â | 43C5 | 175-181 | L | Monoclonal | Mouse recPrP | Dr Horiuchi [33] |
C-terminal region | T4 | 221-239 | L | Polyclonal | Cattle recPrP | Dr Sata [35] |
| Â | F99/97.6.1 | 229-235 | L | Monoclonal | Cattle recPrP | VMRD |