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Table 1 Overview of HI titers at challenge, virus isolation data, clinical symptoms, and mortality rates

From: A single vaccination of commercial broilers does not reduce transmission of H5N1 highly pathogenic avian influenza

 

Number of birds

 

Mean HI titer (absolute (sd))

with HI titer ≥

2^5

at challenge

shedding virus a

with clincial

symptoms

that died

Exp.

Treatment

at challenge

( 2 log)

at end d

( 2 log)

I b

C b

I

C

I

C

I

C

1

no vaccination

challenge at d28 of age

1.6 (1.0)

206 (457)

0

0

22

19

22

22

22

16

2

vaccination at d1

challenge at d28 of age

1.7 (1.3)

166 (381)

0

0

22

18

19

16

16

15

3

vaccination at d10

challenge at d28 of age

1.8 (0.9)

251 (357)

0

0

18

15

16

10

13

7

4

no vaccination

challenge at day 1 of age

4.9 (1.2)c

1.0 (0.4)f

Ndc

nd

16

6

19

19

13

1

  1. a total numbers in each group were 22 inoculated chickens and 22 contact-exposed chickens.
  2. b I: inoculated chickens; C: contact-exposed chickens.
  3. c not determined.
  4. d only from surviving and infected birds.
  5. e from surplus birds.
  6. f one bird had a titer of 1024, which is omitted from this average.