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Table 3 Transcription profile of genes during a primary infection with O.ostertagi

From: Infection with the gastrointestinal nematode Ostertagia ostertagi in cattle affects mucus biosynthesis in the abomasum

Gene    Infectionb
  6 dpi 9 dpi 24 dpi 60 dpe
Mucins     
Membrane bound     
MUC1 2.07 ± 0.3* 2.93 ± 0.3* 3.29 ± 0.3* 2.75 ± 0.2*
MUC20 2.78 ± 0.5* 1.50 ± 0.2* 3.99 ± 0.6* 3.28 ± 0.6*
Secreted gel forming     
MUC2 n.dc n.d n.d n.d
MUC5AC 4.08 ± 1.1* 2.25 ± 0.5* 1.50 ± 0.2* 1.56 ± 0.7*
MUC5B n.d n.d n.d n.d
MUC6 3.09 ± 1.0* 2.80 ± 0.4* 4.39 ± 1.4* 4.52 ± 0.5*
Trefoil Factors     
TFF1 3.89 ± 1.5* 3.32 ± 0.8* 2.57 ± 0.2* 3.90 ± 0.5*
TFF2 2.50 ± 1.1* 4.12 ± 2.4* 2.22 ± 0.8* 3.81 ± 1.4*
TFF3 2.59 ± 0.8* 18.57 ± 11.7* 58.57 ± 13.2* 49.28 ± 16.7*
Glycosyltransferases     
Core structure     
GCNT3 2.93 ± 0.6* 3.73 ± 0.3* 5.90 ± 1.0* 4.29 ± 0.6*
GCNT4 2.92 ± 0.3* 2.33 ± 0.2* 3.02 ± 0.2* 3.14 ± 0.3*
C1GALT1 3.06 ± 0.6* 2.09 ± 0.2* 2.22 ± 0.5* 2.35 ± 0.2*
Backbone and terminal     
GCNT2 2.87 ± 0.8* 1.60 ± 0.2 12.44 ± 4.2* 6.74 ± 1.0*
A4GNT 3.32 ± 0.3* 2.03 ± 0.3 3.12 ± 0.8* 2.75 ± 0.1*
B3GNT3 4.51 ± 1.1* 3.11 ± 0.6* 2.57 ± 0.8* 4.61 ± 0.4*
Sulfotransferases     
H3ST1 1.14 ± 0.2* 2.10 ± 0.6* 4.52 ± 2.6* 2.35 ± 0.5*
H3ST2 n.d n.d n.d n.d
GAL3ST1 n.d n.d n.d n.d
Sialyltransferases     
ST3GAL4 1.60 ± 0.1* 1.20 ± 0.2* 1.89 ± 0.3* 1.15 ± 0.1*
Fucosyltransferases     
FUT1 1.94 ± 0.5* 1.27 ± 0.2* 0.77 ± 0.1* 1.33 ± 0.1*
FUT2 2.35 ± .4* 2.56 ± 0.8* 3.13 ± 0.4* 3.15 ± 0.2*
FUT4 2.77 ± 0.5* 2.89 ± 1.0* 3.09 ± 0.5* 3.13 ± 0.6*
FUT10 1.65 ± 0.2* 1.47 ± 0.2* 1.46 ± 0.2* 1.58 ± 0.1*
Disulphide isomerase     
AGR2 3.41 ± 0.6* 3.44 ± 0.4* 5.82 ± 0.9* 5.24 ± 0.8*
PDIA3 3.16 ± 0.3* 2.60 ± 0.4* 4.12 ± 1.0* 4.46 ± 0.6*
PDIA4 2.58 ± 0.2* 3.51 ± 0.8* 6.95 ± 0.9* 5.37 ± 0.9*
  1. a
  2. amean ± error standard of fold changes in infected animals compared to control (0 dpi).
  3. bdpi: days post-infection dpe: days post-exposure.
  4. cn.d.: not determined, too low in the sample.
  5. *p value ≤ 0.05 control 0 dpi vs infected animals (6, 9, 24 dpi; 60 dpe).