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Figure 4 | Veterinary Research

Figure 4

From: Biphasic activation of PI3K/Akt and MAPK/Erk1/2 signaling pathways in bovine herpesvirus type 1 infection of MDBK cells

Figure 4

Virus production was significantly reduced by the inhibition of PI3k/Akt pathway (a) but not by MAPK/Erk1/2 pathway (b). (a) Growth arrested MDBK cells mock pretreated or pretreated with 10 μM Ly294002 were infected with BoHV-1 virus in the medium with or without Ly294002. After 24 h incubation the virus production were titrated. (b) Growth arrested MDBK cells mock pretreated or pretreated with 10 μM U0126 were infected with BoHV-1 virus in the medium with or without U0126. After 24 h incubation the virus production were titrated. Experiments were repeated three times, and the error bars indicate the standard deviations of three independent experiments.

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Veterinary Research

ISSN: 1297-9716