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Table 1 Genes associated with pH homeostasis, chemotaxis, adhesion to epithelial cells, and oxidative stress resistance in the genome of H. suis type strain 1 (HS1T) and H. suis strain 5 (HS5).

From: Genome sequence of Helicobacter suis supports its role in gastric pathology

Group Gene detected in HS1T Gene detected in HS5 Description of homolog Percentage of sequence aligned (of which % conserved) with described homolog1
pH homeostasis HSUHS1_0708 HSUHS5_0286 Urease subunit alfa (ureA) of H. heilmannii 100 (94)
  HSUHS1_0707 HSUHS5_0285 Urease subunit beta (ureB) of H. heilmannii 100 (94)
  HSUHS1_0706 HSUHS5_0284 Urease transporter (ureI) of H. felis 100 (89)
  HSUHS1_0705 HSUHS5_0283 Urease accessory protein (ureE) of H. bizzozeronnii 100 (84)
  HSUHS1_0704 HSUHS5_0282 Urease accessory protein (ureF) of H. bizzozeronnii 100 (84)
  HSUHS1_0702 HSUHS5_0280 Urease accessory protein (ureH) of H. bizzozeronnii 96 (84)
  HSUHS1_0703 HSUHS5_0281 Urease accessory protein (ureG) of H. bizzozeronnii 100 (95)
  HSUHS1_0133 HSUHS5_0547 Hydrogenase expression/formation protein (hypA) of H. pylori 98 (83)
  HSUHS1_0615 HSUHS5_0817 Hydrogenase expression/formation protein (hypB) of H. pylori 99 (91)
  HSUHS1_0616 HSUHS5_0816 Hydrogenase expression/formation protein (hypC) of H. pylori 98 (89)
  HSUHS1_0617 HSUHS5_0815 Hydrogenase expression/formation protein (hypD) of H. achinonychis 98 (80)
  HSUHS1_0081 HSUHS5_1197 l-Asparaginase II (ansB) of H. pylori 98 (64)
  HSUHS1_0230 HSUHS5_1130 Arginase (rocF) of H. pylori 99 (75)
  HSUHS1_0888 HSUHS5_0231 Acylamide amidohydrolase (amiE) of H. pylori 100 (93)
  HSUHS1_0680 HSUHS5_0265 Formamidase (amiF) of H. pylori 100 (98)
  HSUHS1_0161 HSUHS5_1077 α-Carbonic anhydrase of H. pylori 92 (69)
  HSUHS1_0391 HSUHS5_0874 Aspartase (aspA) of H. acinonychis 100 (89)
Chemotaxis HSUHS1_1004 HSUHS5_0649 CheA-MCP interaction modulator of H. pylori 99 (79)
  HSUHS1_1003 - Bifunctional chemotaxis protein (cheF) of H. pylori 82 (86)
  HSUHS1_1002 HSUHS5_0775 Purine-binding chemotaxis portein (cheW) of H. pylori 98 (91)
  HSUHS1_0538 HSUHS5_0706 Chemotaxis protein (cheV) of H. pylori 100 (92)
  HSUHS1_0846 HSUHS5_0081 Putative chemotaxis protein of H. pylori 100 (79)
  HSUHS1_0299 HSUHS5_0250 Chemotaxis protein (cheY) of H. pylori 100 (95)
  HSUHS1_1001 HSUHS5_0774 Methyl-accepting chemotaxis protein (tlpA) of H. pylori 100 (60)
  HSUHS1_0286 HSUHS5_0256 Methyl-accepting chemotaxis protein ( tlpB) of H. pylori 98 (63)
  HSUHS1_0479 HSUHS5_0476 Methyl- accepting chemotaxis protein of H. acinonychis 100 (66)
  HSUHS1_0196 HSUHS5_0122 Methyl- accepting chemotaxis protein of Campylobacter upsaliensis 2 99 (53)
  HSUHS1_0141 HSUHS5_0641 Methyl- accepting chemotaxis protein of Campylobacter fetus subsp. fetus 2 99 (64)
  HSUHS1_0763 - Methyl- accepting chemotaxis protein of Methylibium petroleiphilum 2 83 (52)
  HSUHS1_0944 HSUHS5_0990 Methyl-accepting chemotaxis sensory transducer Marinomonas sp.2 57 (59)
Adhesion HSUHS1_0666 HSUHS5_1053 Outer membrane protein (horB) of H. pylori 100 (63)
  HSUHS1_0354 HSUHS5_0398 Neuraminyllactose-binding hemagglutinin (hpaA) of H. acinonychis 94 (77)
Oxidative stress resistance HSUHS1_1147 HSUHS5_0608 Catalase (katA) of H. acinonychis 95 (82)
  HSUHS1_0549 HSUHS5_1206 Mismatch repair ATPase (mutS) of H. hepaticus 99 (60)
  HSUHS1_0163 HSUHS5_0495 Superoxide dismutase (sodB) of H. pylori 100 (90)
  HSUHS1_1186 HSUHS5_0005 Bacterioferritin co-migratory protein of H. hepaticus 99 (72)
  HSUHS1_0683 HSUHS5_0262 NAD(P)H quinone reductase (mdaB) of Campylobacter fetus subsp. fetus 97 (68)
  HSUHS1_0689 HSUHS5_0268 Peroxiredoxin of H. pylori 3 100 (92)
  1. 1 Resulting from tblastn-based cross-mapping of the H. pylori proteome to the H. suis HS1T and HS5 genomes and blastp-based ab initio analyses of the translated H. suis HS1T and HS5 ORFs against the Uniprot-KB universal protein database. Differences between HS1T and HS5 homologs ≤ 1%.
  2. 2 Lacking in other Helicobacter genomes available at GenBank.
  3. 3 Member of the 2-Cys peroxiredoxin superfamily.