Table 1 Genes associated with pH homeostasis, chemotaxis, adhesion to epithelial cells, and oxidative stress resistance in the genome of H. suis type strain 1 (HS1T) and H. suis strain 5 (HS5).
From: Genome sequence of Helicobacter suis supports its role in gastric pathology
Group | Gene detected in HS1T | Gene detected in HS5 | Description of homolog | Percentage of sequence aligned (of which % conserved) with described homolog1 |
|---|---|---|---|---|
pH homeostasis | HSUHS1_0708 | HSUHS5_0286 | Urease subunit alfa (ureA) of H. heilmannii | 100 (94) |
| Â | HSUHS1_0707 | HSUHS5_0285 | Urease subunit beta (ureB) of H. heilmannii | 100 (94) |
| Â | HSUHS1_0706 | HSUHS5_0284 | Urease transporter (ureI) of H. felis | 100 (89) |
| Â | HSUHS1_0705 | HSUHS5_0283 | Urease accessory protein (ureE) of H. bizzozeronnii | 100 (84) |
| Â | HSUHS1_0704 | HSUHS5_0282 | Urease accessory protein (ureF) of H. bizzozeronnii | 100 (84) |
| Â | HSUHS1_0702 | HSUHS5_0280 | Urease accessory protein (ureH) of H. bizzozeronnii | 96 (84) |
| Â | HSUHS1_0703 | HSUHS5_0281 | Urease accessory protein (ureG) of H. bizzozeronnii | 100 (95) |
| Â | HSUHS1_0133 | HSUHS5_0547 | Hydrogenase expression/formation protein (hypA) of H. pylori | 98 (83) |
| Â | HSUHS1_0615 | HSUHS5_0817 | Hydrogenase expression/formation protein (hypB) of H. pylori | 99 (91) |
| Â | HSUHS1_0616 | HSUHS5_0816 | Hydrogenase expression/formation protein (hypC) of H. pylori | 98 (89) |
| Â | HSUHS1_0617 | HSUHS5_0815 | Hydrogenase expression/formation protein (hypD) of H. achinonychis | 98 (80) |
| Â | HSUHS1_0081 | HSUHS5_1197 | l-Asparaginase II (ansB) of H. pylori | 98 (64) |
| Â | HSUHS1_0230 | HSUHS5_1130 | Arginase (rocF) of H. pylori | 99 (75) |
| Â | HSUHS1_0888 | HSUHS5_0231 | Acylamide amidohydrolase (amiE) of H. pylori | 100 (93) |
| Â | HSUHS1_0680 | HSUHS5_0265 | Formamidase (amiF) of H. pylori | 100 (98) |
|  | HSUHS1_0161 | HSUHS5_1077 | α-Carbonic anhydrase of H. pylori | 92 (69) |
| Â | HSUHS1_0391 | HSUHS5_0874 | Aspartase (aspA) of H. acinonychis | 100 (89) |
Chemotaxis | HSUHS1_1004 | HSUHS5_0649 | CheA-MCP interaction modulator of H. pylori | 99 (79) |
| Â | HSUHS1_1003 | - | Bifunctional chemotaxis protein (cheF) of H. pylori | 82 (86) |
| Â | HSUHS1_1002 | HSUHS5_0775 | Purine-binding chemotaxis portein (cheW) of H. pylori | 98 (91) |
| Â | HSUHS1_0538 | HSUHS5_0706 | Chemotaxis protein (cheV) of H. pylori | 100 (92) |
| Â | HSUHS1_0846 | HSUHS5_0081 | Putative chemotaxis protein of H. pylori | 100 (79) |
| Â | HSUHS1_0299 | HSUHS5_0250 | Chemotaxis protein (cheY) of H. pylori | 100 (95) |
| Â | HSUHS1_1001 | HSUHS5_0774 | Methyl-accepting chemotaxis protein (tlpA) of H. pylori | 100 (60) |
| Â | HSUHS1_0286 | HSUHS5_0256 | Methyl-accepting chemotaxis protein ( tlpB) of H. pylori | 98 (63) |
| Â | HSUHS1_0479 | HSUHS5_0476 | Methyl- accepting chemotaxis protein of H. acinonychis | 100 (66) |
| Â | HSUHS1_0196 | HSUHS5_0122 | Methyl- accepting chemotaxis protein of Campylobacter upsaliensis 2 | 99 (53) |
| Â | HSUHS1_0141 | HSUHS5_0641 | Methyl- accepting chemotaxis protein of Campylobacter fetus subsp. fetus 2 | 99 (64) |
| Â | HSUHS1_0763 | - | Methyl- accepting chemotaxis protein of Methylibium petroleiphilum 2 | 83 (52) |
| Â | HSUHS1_0944 | HSUHS5_0990 | Methyl-accepting chemotaxis sensory transducer Marinomonas sp.2 | 57 (59) |
Adhesion | HSUHS1_0666 | HSUHS5_1053 | Outer membrane protein (horB) of H. pylori | 100 (63) |
| Â | HSUHS1_0354 | HSUHS5_0398 | Neuraminyllactose-binding hemagglutinin (hpaA) of H. acinonychis | 94 (77) |
Oxidative stress resistance | HSUHS1_1147 | HSUHS5_0608 | Catalase (katA) of H. acinonychis | 95 (82) |
| Â | HSUHS1_0549 | HSUHS5_1206 | Mismatch repair ATPase (mutS) of H. hepaticus | 99 (60) |
| Â | HSUHS1_0163 | HSUHS5_0495 | Superoxide dismutase (sodB) of H. pylori | 100 (90) |
| Â | HSUHS1_1186 | HSUHS5_0005 | Bacterioferritin co-migratory protein of H. hepaticus | 99 (72) |
| Â | HSUHS1_0683 | HSUHS5_0262 | NAD(P)H quinone reductase (mdaB) of Campylobacter fetus subsp. fetus | 97 (68) |
| Â | HSUHS1_0689 | HSUHS5_0268 | Peroxiredoxin of H. pylori 3 | 100 (92) |