Table 1 Genes that control the immune response to L. donovani/L. infantum infection.

Innate intraphagosomal control of infection in the spleen and the liver

Slc11a1

1

[40–44]

Influences antigen presentation during the acquired immune response in the splen, the liver and the bone marrow

H2

17

[43, 45]

Formation of hepatic granulomas. Acquired immune response

Ir2

2

[43]

Influences resistance to parasites in the spleen. C57BL/6J bg/bg mice expressed deficient natural killer cell activity and failed to eliminate L. donovani amastigotes

Lyst/Beige

13

[46]