External lesions observed in Syrian hamsters infected with 107 L. infantum promastigotes at seven months pi. (A-B) Mucocutaneous lesions localized in the snout. (C) Ulcers on the back of the hamsters. The isolate M/CAN/ES/96/BCN150 (zymodeme MON-1) of L. infantum was used for infection experiments. This strain was maintained in our laboratory by passage in Syrian hamsters.