Table 3 Summary of published data and modelled distributions of the quantities of Mycobacterium avium subsp. paratuberculosis (Map) shed, depending on the health state (X) and the route of transmission (r) in a Map infection dynamics model within a structured dairy herd

Minimal value

Maximal value

Mean value

Source

F( X ,r)

Map direct shedding in milk and colostrum (Map/L)

Subclinically infected

2.2 × 10⁴

8.8 × 10⁴

5 × 10⁴

[39]

10⁵ × beta(8,8)

Clinically affected

-

-

5 × 10⁴

[42]

10⁵ × beta(8,8)

Map indirect shedding in milk and colostrum (faecal contamination) (Map/L)

Subclinically infected

0

2 × 10¹⁰

40

[43, 44]

1 + 10³ × beta(1,25)

Clinically affected

700

2 × 10¹⁰

14 × 10⁴

[43, 44]

10^{(3 + 10 × beta(50,200))}

Map shedding in faeces (Map/kg)

Transiently infectious

6 × 10⁴

6.3 × 10⁵

3 × 10⁵

[9]

10⁶ × beta(8.8,19)

Subclinically infected

10⁴

10¹⁵

2.6 × 10⁶

[45]

10^{(4 + 10 × beta(2.65,17))}

Clinically affected

10⁸

10¹⁵

10¹⁰

[26, 46]

10^{(8 + 10 × beta(2,17))}