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Table 3 Bioassay of different localizations of bovine small intestine in bovine transgenic mice (Tgbov XV): results (revealed by PTA-Immunoblot), transmission rates and incubation periods

From: BSE infectivity in jejunum, ileum and ileocaecal junction of incubating cattle

Months p.i. Cow Localization
   Jejunum A Jejunum B Ileum Ileocaec.
  IT 14 0/10
--
0/14
--
9/13
280 ± 41
0/15
--
8 IT 20 0/14*
--
0/13
--
8/11
334 ± 61
0/15*
--
  IT 39 1/14*
502
0/12*
--
7/11*
310 ± 49
0/12
--
  IT 55 2/10*
379, 522
0/12
--
7/9
332 ± 47
3/13
442, 517, 582
12 IT 01 0/14*
--
3/10
407, 432, 600
12/13
305 ± 45
14/15
315 ± 40
  IT 16 0/13
--
0/12
--
6/11
412 ± 31
1/10
395
  IT 06 0/12
--
1/13
375
10/10
279 ± 47
12/12
277 ± 39
  IT 57 0/15
--
2/10
393, 428
11/11
260 ± 55
9/11
297 ± 64
  IT 07 0/14*
--
0/15
--
0/12*
--
0/9
--
16 IT 28 0/11
--
0/11
--
0/11
--
0/12
--
  IT 46 0/11
--
0/12
--
0/10
--
0/12
--
  IT 65 0/12
--
0/11
--
11/14*
319 ± 41
13/13*
349 ± 53
20 IT 10 0/13
--
2/15
363, 408
0/11*
--
0/9
--
  IT 17 0/12*
--
0/10
--
0/15*
--
12/12
311 ± 33
  IT 50 0/12*
--
0/14*
--
11/13
353 ± 57
0/12*
--
  IT 60 1/12
391
0/9
--
11/12
345 ± 37
0/12
--
  1. The first line indicates the number of positive tested mice/total number of mice, the second line indicates the mean incubation period in days post infection
  2. * augmented groups - additional inoculations after heating the inoculum to 70°C for 10 min