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Figure 2 | Veterinary Research

Figure 2

From: Mesenteric lymph node cells from neonates present a prominent IL-12 response to CpG oligodeoxynucleotide via an IL-15 feedback loop of amplification

Figure 2

Age-dependent IL-12 responses. MLN and spleen cells from 6- to 14-day-old neonates (closed circles), 20-day-old lambs (closed diamonds) and adults (open squares) were cultured in vitro for 48 h, with 1 μM CpG-2006 or 1 μM Ctl-ODN. At the end of the culture period, supernatants were harvested and ELISA carried out to assay IL-12 secreted by MLN cells (A) or spleen cells (B). Medians are shown for each stimulus. * p ≤ 0.01; ** p ≤ 0.001; *** p ≤ 0.0005.

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Veterinary Research

ISSN: 1297-9716