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Table 1 Properties of recombinant NDV strains: F protein cleavage site and virulence.

From: Virulence of newcastle disease virus: what is known so far?

Virus

Parent

Cleavage site

ICPI

IVPI

Reference

NDFL

LaSota

GRQGRL

0.00

0.00

[43]

NDFLtag*

LaSota

RRQRRF

1.28

0.76

[43, 67]

NDFL(F) H

LaSota

RRQRRF

1.31

0.41

[49]

rLaSota

LaSota

GRQGRL

0.00

0.00

[42]

rLaSota V.F.*

LaSota

RRQKRF

1.12

0.00

[62]

rNDV

Clone 30

GRQGRL

0.01

 

[63]

rNDVF1*

Clone 30

RRQKRF

1.28

 

[63]

NDV/ZJ1

ZJ1

RRQKRF

1.88

2.80

[50]

NDV/ZJ1FM†

ZJ1

GRQERL

0.13

0.00

[64]

FL-Herts

Herts/33

RRQRRF

1.63

2.29

[49]

rgAV324

AV324/96

RRKKRF

0.10

0.00

[46]

FL-Herts(F) AV

Herts/33

RRKKRF

1.56

 

[46]

rgAV324(F) H

AV324/96

RRQRRF

0.00

 

[46]

  1. * lentogenic cleavage site motif modified into velogenic cleavage site motif.
  2. † velogenic cleavage site motif modified into lentogenic cleavage site motif.
  3. Superscript H: F gene originating from strain Herts/33.
  4. Superscript AV: F gene originating from strain AV324/96.