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Figure 3 | Veterinary Research

Figure 3

From: Theileria annulata-transformed cell lines are efficient antigen-presenting cells for in vitro analysis of CD8 T cell responses to bovine herpesvirus-1

Figure 3

Specificity of CD8 T cell clones generated from PBMC of a T. parva -immune animal by in vitro stimulation with autologous T. annulata -transformed cells infected with Tp1 canarypox. Forty-eight CD8 T cell clones were analysed for cytotoxicity in a 4-hour 111Indium release assay using as targets autologous T. annulata tranformed cells alone (a) or pulsed with a peptide representing a dominant epitope (Tp1214-224) in the Tp1 antigen (Tp1) (b). The majority of clones are specific for Tp1214-225.

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