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Table 3 Percentage frequencies of polymorphisms in the caprine Prnp open reading frame in UK farms.

From: Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom

Herd A$ B$ C D E$ F G H I X J$ K L M P Q R S T
Breed Category Dairy Dairy
Meat
Fiber Fiber
Meat
Meat Other
Breed S, T, A, N S, A S, T S, T S S S, A S, T, A, N S S, T S, B Ag Ag Ag, C, B B B B GG F
Number 323 188 20 39 91 35 23 29 48 41 97 29 22 35 103 21 29 12 10
wt-P & wt-S 62.9 50.8 50 60.2 59.3 57.1 76.2 96.6 61.5 75.7 63.4 96.6 95.5 75.7 52.4 57.1 69 16.7 100
R101 - 0.5 - - - - - - - - - - - - - - - - -
S127 5.3 25.5 10 - 3.3 4.3 4.3 - - 2.4 3.1 - - - - 2.4 - - -
M142 29.1 23.2 32.5 37.2 33 27.1 15.2 - 37.5 19.5 20.8 1.7 - 1.4 19.4 2.4 - - -
R143 - - - - - - - 3.4 - - - 1.7 4.5 8.6 2.9 2.4 12 - -
S146 - - 7.5 - - - - - - - 4.1 - - 4.3 23.3 33.3 19 - -
H154 - - - - - - - - - - - - - 1.4 0.5 - - - -
Q211 1.9 - - 1.3 3.3 8.6 4.3 - 1 2.4 6.8 - - - - 2.4 - 50 -
L218 - - - - - - - - - - - - - 8.6 1.5 - - - -
K222 0.8 - - 1.3 1.1 2.9 - - - - 1.6 - - - - - - 33.3 -
  1. Breeds: A = Alpine, Ag = Angora, B = Boer, C = Cashmere, GG = Golden Guernsey, N = Anglo-Nubian, S = Saanen, T = Toggenburg, F = Feral; number = number of animals, for calculation of allele frequency this is doubled to get number of chromosomes. For codon 101 only 2350 chromosomes were recorded and for codon 127 only 2362. X represents five farms each ≤ 12 animals. $scrapie-affected herds.