Skip to main content
Figure 1 | Veterinary Research

Figure 1

From: Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade

Figure 1

Cloning of bovine PD-L1. A: Nucleotide and deduced amino acid sequences of bovine PD-L1 cDNA. Bovine PD-L1 cDNA has an open reading frame extending from positions 61 to 930 and encodes for a 290 aa polypeptide. The putative signal peptide and polyadenylation signal are underlined with dotted and solid lines, respectively. B: Alignment of deduced amino acid sequences of vertebrate PD-L1. Bold line indicates the transmembrane domain (238-259) of bovine PD-L1. C: Phylogenetic tree constructed from nucleotide sequences of vertebrate PD-L1 by the Mega 4 software. The bootstrap values supporting a particular cluster are shown within the node. Numbers indicate the bootstrap percentage (100 replicates). The scale indicates the divergence time. Clusters were identified based on their Order.

Back to article page

Veterinary Research

ISSN: 1297-9716