Genome analysis of Streptococcus spp. isolates from animals in pre-antibiotic era with respect to antibiotic susceptibility and virulence gene profiles

Table 4 Virulence gene profiles of S. pyogenes isolates from 1940s analyzed in this study (n = 7)

Strains	Adherence								Anti-proteolysis							Exoenzyme						Immune evasion		Toxin
Strains	cpa	fbaA	fbaB	fctA	fctB	lepA	lmb	srtC1	grab	emm	hasA	hasB	hasC	ideS/mac	sic	hylP	mf/spd	mf2	mf3	sda	speB	scpA	ska	fbp54	slo	smeZ	spea	spec	speg	speh	spei	spej	spek	spel	spem	ssa
S. pyogenes_12							+				+	+	+	+		+	+	+			+	+	+	+	+	+		+	+	+	+
S. pyogenes_14	+			+	+	+	+	+	+		+	+	+	+				+	+			+	+	+	+	+		+	+	+	+	+
S. pyogenes_15	+	+	+				+				+	+	+	+		+	+		+		+	+	+	+	+	+	+		+	+
S. pyogenes_5							+							+		+	+	+	+		+	+	+	+	+	+		+								+
S. pyogenes_6	+			+	+	+	+	+	+	+	+	+	+	+	+		+	+	+		+	+	+	+	+	+		+	+	+	+	+
S. pyogenes_7	+						+				+	+	+	+			+				+	+	+	+	+	+			+
S. pyogenes_9	+			+	+	+	+	+	+	+	+	+	+	+	+		+	+	+		+	+	+	+	+	+		+	+	+	+	+

ISSN: 1297-9716